Hymenialdisine Methanoate

CAS: 82005-12-7 84094-94-0

Ref. TR-H998000

Produktinformation

• Name: Hymenialdisine Methanoate
• Synonyme: (4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one Methanoate, (Z)-Hymenialdisine Methanoate

Beschreibung

Applications A potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product.
References Cheetham, G., et al.: J. Biol. Chem., 277, 42419 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Sharma, V., et al.: Bioorg. Med. Chem. Lett., 14, 4319 (2004), Anamika, et al.: Proteins, 58, 180 (2005), Birault, V., et al.: Curr. Med. Chem., 13, 1735 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 324.13 + x(32.04)
• Formel: C₁₁H₁₀BrN₅O₂·x(CH₄O)
• Farbe/Form: Neat