(1R)-1-Phenyl-1,3-propanediol

CAS: 103548-16-9

Ref. TR-P103540

Produktinformation

• Name: (1R)-1-Phenyl-1,3-propanediol
• Synonyme: (1R)-1-phenylpropane-1,3-diol, (R)-Phenyl-1,3-Propanediol

Beschreibung

Applications (1R)-1-Phenyl-1,3-propanediol is used in the synthesis and characterization of cytochrome P450 3A-activated prodrugs which are useful for targeting phosph(on)ate-based drugs to liver. It is also used in the synthesis of 1,3-diols by diarylprolinol-catalyzed aldol reaction of acetaldehyde with aldehydes followed by reduction.
References Erion, Mark D., et al.: J. Am. Chem. Soc., 126, 5154(2004); Hayashi, Yujiro, et al.: Angewandte Chemie Int. Ed., 47, 2082(2008)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 152.19
• Formel: C₉H₁₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C9H12O2/c10-7-6-9(11)8-4-2-1-3-5-8/h1-5,9-11H,6-7H2/t9-/m1/s1
• InChI Key: InChIKey=RRVFYOSEKOTFOG-SECBINFHSA-N
• SMILES: OCC[C@@H](O)c1ccccc1