(S)-Tenofovir

CAS: 147127-19-3

Ref. TR-T018480

Produktinformation

• Name: (S)-Tenofovir
• Synonyme: [(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid, Phosphonic acid, [[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, (S)-(1-(6-Amino-9H-Purin-9-Yl)Propan-2-Yloxy)Methylphosphonic Acid

Beschreibung

Applications (S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts.
References Balzarini, J. et al: Biochem. Biophys. Res. Comm., 219, 337 (1996); Balzarini, J. et al.: Antimicrob. Agents. Ch., 37, 332 (1993); Thormar, H. et al.: Antimicorb. Agents. Ch., 37, 2540 (1993)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 287.21
• Formel: C₉H₁₄N₅O₄P
• Farbe/Form: Neat
• InChl: InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1
• InChI Key: InChIKey=SGOIRFVFHAKUTI-LURJTMIESA-N
• SMILES: C[C@@H](Cn1cnc2c(N)ncnc21)OCP(=O)(O)O