CAS 10016-20-3

α-Ciclodextrina

Descripción:

α-Ciclodextrina es un oligosacárido cíclico compuesto por seis unidades de glucosa unidas por enlaces α-1,4-glicosídicos, formando una estructura toroidal. Es un polvo blanco y cristalino que es soluble en agua, con una solubilidad que aumenta con la temperatura. Este compuesto es conocido por su capacidad para formar complejos de inclusión con diversas moléculas hidrofóbicas, mejorando su solubilidad y estabilidad, lo que lo hace valioso en aplicaciones farmacéuticas, alimentarias y cosméticas. α-Ciclodextrina tiene un perfil de toxicidad relativamente bajo y se reconoce generalmente como seguro (GRAS) para el consumo. Su estructura única le permite encapsular moléculas huésped dentro de su cavidad hidrofóbica, facilitando la liberación controlada y mejorando la biodisponibilidad. Además, α-Ciclodextrina exhibe propiedades como biodegradabilidad y la capacidad de modificar los perfiles de liberación de ingredientes activos, lo que lo convierte en un excipiente versátil en la formulación de medicamentos. Sus aplicaciones se extienden más allá de los productos farmacéuticos a áreas como la conservación de alimentos y la mejora del sabor, mostrando su naturaleza multifuncional en diversas industrias.

Fórmula: C₃₆H₆₀O₃₀

InChI: InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1

Clave InChI: InChIKey=HFHDHCJBZVLPGP-RWMJIURBSA-N

SMILES: C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H]

Sinónimos:

• (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol (non-preferred name)
• (1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol (non-preferred name)
• 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26]dotetracontane, α-cyclodextrin deriv.
• 5,10,15,20,25,30-Hexakis(Hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]Dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-Dodecol (Non-Preferred Name)
• Alpha-Cycloamylose
• Alpha-Dextrin
• Cavamax W 6
• Cavamax W 6 Food
• Celdex A 100
• Ciclohexapentilosa
• Cyclohexaamylose
• Cyclohexaamylose hydrate
• Cyclohexadextrin
• Cyclohexapentylose
• Cyclomaltohexaose
• Cyclomaltohexose
• Dexipar α-100
• Dextrin, α-cyclo
• Dexy Pearl α-100
• Isoeleat K 50
• Nsc 269470
• Ringdex A
• Stereoisomer of 5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
• Stereoisomer of 5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
• alpha-Cyclodextrin
• Α-100
• α-Cycloamylose
• α-Cyclodextrin
• α-Dextrin
• α-Schardinger dextrin

α-Cyclodextrin

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀

Pureza: >98.0%(HPLC)

Forma y color: White powder to crystal

Peso molecular: 972.85

Ref: 3B-C0776

α-Cyclodextrin, 97+%

CAS: 10016-20-3

Useful for selective precipitation of enantiomeric, positional or structural isomers

Fórmula: C₃₆H₆₀O₃₀

Pureza: 97+%

Forma y color: White to pale cream, Crystalline powder

Peso molecular: 972.85

Ref: 02-J60687

ALFADEX CRS

CAS: 10016-20-3

ALFADEX CRS

Fórmula: C₃₆H₆₀O₃₀

Forma y color: Amorphous. White. Whitish. Crystalline Powder. Powder.

Peso molecular: 972.8436

Ref: 41-A1225000

α Cyclodextrin

CAS: 10016-20-3

Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose; sugar ethers and sugar esters, and their salts, nesoi

Fórmula: C₃₆H₆₀O₃₀

Forma y color: White Off-White Crystalline Powder Amorphous Powder

Peso molecular: 972.31694

Ref: 45-1154558

α-cyclodextrin

CAS: 10016-20-3

α-cyclodextrin

Fórmula: C₃₆H₆₀O₃₀

Pureza: By hplc: 99.5% (Typical Value in Batch COA)

Forma y color: Solid

Peso molecular: 972.8436

Ref: 54-BIM1014

α-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin

Fórmula: C₃₆H₆₀O₃₀

Pureza: By hplc: coforms witrh reference (Typical Value in Batch COA)

Forma y color: White Solid-Powder

Peso molecular: 972.8436

Ref: 54-BIB6038

a-Cyclodextrin

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀

Pureza: 97%

Forma y color: Solid

Peso molecular: 972.8436

Ref: IN-DA00H969

α-Cyclodextrin, Ph. Eur. grade

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀·xH₂O

Pureza: (dried basis) 98.0 - 101.0 %

Forma y color: White or almost white, amorphous or crystalline powder

Peso molecular: 972.86

Ref: 7W-GP9262

Sugammadex Impurity 62 (α-Cyclodextrin)

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀

Forma y color: White To Off-White Solid

Peso molecular: 972.85

Ref: 4Z-S-082005

α-Cyclodextrin

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀·xH₂O

Pureza: ≥ 98%

Forma y color: White powder

Peso molecular: 972.86

Ref: 7W-GC6443

α-Cyclodextrin

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀

Forma y color: Neat

Peso molecular: 972.84

Ref: 04-C11821100

α-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.

Fórmula: C₃₆H₆₀O₃₀

Pureza: 99.79% - 99.9%

Forma y color: White Solid

Peso molecular: 972.84

Ref: TM-T17303

α-Cyclodextrin

CAS: 10016-20-3

Fórmula: C₃₆H₆₀O₃₀

Peso molecular: 972.84

Ref: ST-EA-CP-C118001

α-Cyclodextrin

Producto controlado

CAS: 10016-20-3

Stability Hygroscopic
Applications α-Cyclodextrin is a 6 member dextrin ring used as an encapsulation agent for bioactive compounds and pharmaceuticals.
References Pinho, E. et al.: Carb. Polym., 101, 121 (2014);

Fórmula: C₃₆H₆₀O₃₀

Forma y color: Neat

Peso molecular: 972.84

Ref: TR-C988470

a-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin is a cyclic oligosaccharide with 6 D-glucose residues which are α-1,4-linked. α-cyclodextrin is used in the food industry to encapsulate flavours and fragrances. α-cyclodextrin is also an effective inhibitor of the upstream inflammatory response induced by cholesterol crystals. Cholesterol crystal-induced complement activation is a critical step in the development of atherosclerosis, thus inhibition of complement with α-cyclodextrin has the potential to be used in the treatment of atherosclerosis.

Fórmula: C₃₆H₆₀O₃₀

Pureza: Min. 98 Area-%

Forma y color: White Off-White Powder

Peso molecular: 972.84 g/mol

Ref: 3D-OC06644

α-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin

Fórmula: C₃₆H₆₀O₃₀

Pureza: 97%

Peso molecular: 972.84

Ref: IN-DG113410

α-Cyclodextrin

CAS: 10016-20-3

Pureza: 97%

Forma y color: Solid

Peso molecular: 972.8460083

Ref: 10-F801970

α-Cyclodextrin Deuterated

Producto controlado

CAS: 10016-20-3

Applications α-Cyclodextrin (C988470) is a 6 member dextrin ring used as an encapsulation agent for bioactive compounds and pharmaceuticals.
References Pinho, E. et al.: Carb. Polym., 101, 121 (2014);

Fórmula: C₃₆H₄₂D₁₈O₃₀

Forma y color: Neat

Peso molecular: 990.95

Ref: TR-C988472

a-Cyclodextrin

CAS: 10016-20-3

α-Cyclodextrin is a cyclic oligosaccharide with 6 D-glucose residues which are α-1,4-linked. α-cyclodextrin is used in the food industry to encapsulate flavors and fragrances (Kfoury, 2016). α-cyclodextrin is also an effective inhibitor of the upstream inflammatory response induced by cholesterol crystals. Cholesterol crystal-induced complement activation is a critical step in the development of atherosclerosis, thus inhibition of complement with α-cyclodextrin has the potential to be used in the treatment of atherosclerosis (Pilely, 2019).

Fórmula: C₃₆H₆₀O₃₀

Pureza: Min. 90.0 Area-%

Peso molecular: 972.84 g/mol

Ref: 3D-C-9100