CAS 100986-89-8
:Ácido Q de levofloxacina
Descripción:
Ácido Q de levofloxacina, con el número CAS 100986-89-8, es un compuesto químico que es un derivado de la levofloxacina, que es un antibiótico fluoroquinolona. Esta sustancia se caracteriza por su capacidad para inhibir la girasa del ADN bacteriano y la topoisomerasa IV, enzimas críticas para la replicación y transcripción del ADN bacteriano. Ácido Q de levofloxacina es típicamente un polvo cristalino blanco a blanco amarillento, soluble en agua y varios disolventes orgánicos, lo que facilita su uso en formulaciones farmacéuticas. Su estructura molecular incluye un núcleo bicíclico con un átomo de flúor, que contribuye a su actividad antibacteriana de amplio espectro contra bacterias tanto Gram-positivas como Gram-negativas. El compuesto se utiliza a menudo en el tratamiento de infecciones del tracto respiratorio, infecciones del tracto urinario e infecciones cutáneas. Además, puede exhibir cierto grado de fototoxicidad y tiene requisitos específicos de almacenamiento para mantener su estabilidad. Al igual que con otras fluoroquinolonas, es esencial monitorear los posibles efectos secundarios, incluidos la tendinitis y los efectos en el sistema nervioso central.
Fórmula:C19H20FN3O6
InChI:InChI=1/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)/t5-/m0/s1
Clave InChI:InChIKey=NVKWWNNJFKZNJO-YFKPBYRVSA-N
SMILES:O=C1C=2C=3N(C=C1C(O)=O)[C@@H](C)COC3C(F)=C(F)C2
Sinónimos:- (3S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
- (3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- (S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
- (S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-
- 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (S)-
- 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-(3S)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
- 9,10-Difluoro-3-(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
- 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- Levofloxacin Q-acid
- Levofloxacin acid
- Levofluorocarboxylic acid
- Levofloxacin carboxylic acid
- 9,10-DIFLUORO-2,3-DIHYDRO-3-(S)-METHYL-7-OXO-7H-PY
- 8,9-difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
- S(-)-9,10-DIFL-2,3-DIHYDRO-3-ME-7H-PYRI&
- (-)-9,10-DIFLUORO-3(S)-METHL-7-OXO-2,3-DIHYDRO-7H-PRYIDO[1,2,3-DE]1,2-BENZOX-AZINE-6-CARBOXYLICACID
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Levofloxacin Q-Acid
CAS:Fórmula:C13H9F2NO4Pureza:>98.0%(HPLC)(T)Forma y color:White to Light yellow powder to crystalPeso molecular:281.21Levofloxacin Related Compound B
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C13H9F2NO4Forma y color:White Off-White Crystalline PowderPeso molecular:281.04996Levofloxacin carboxylic acid
CAS:Levofloxacin carboxylic acidFórmula:C13H9F2NO4Pureza:>98%Peso molecular:281.21Levofloxacin EP Impurity F (Levofloxacin USP Related Compound B)
CAS:Fórmula:C13H9F2NO4Forma y color:Off-White SolidPeso molecular:281.21(3S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
CAS:Fórmula:C13H9F2NO4Pureza:98%Forma y color:SolidPeso molecular:281.2117Levofloxacin carboxylic acid
CAS:Levofloxacin carboxylic acid is a fluoroquinolone compound used in biochemical experiments and drug synthesis research.Fórmula:C13H9F2NO4Pureza:99.10%Forma y color:SolidPeso molecular:281.2117(S)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
CAS:Fórmula:C13H9F2NO4Forma y color:NeatPeso molecular:281.21Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
CAS:Producto controladoImpurity Levofloxacin USP Related Compound B
Applications Levofloxacin intermediate.
References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),Fórmula:C13H9F2NO4Forma y color:NeatPeso molecular:281.21(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
CAS:Fórmula:C13H9F2NO4Peso molecular:281.21(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
CAS:Fórmula:C13H9F2NO4Pureza:95%Forma y color:SolidPeso molecular:281.215Levofloxacin carboxylic acid
CAS:(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acidFórmula:C13H9F2NO4Pureza:97%Peso molecular:281.21Levofloxacin carboxylic acid
CAS:Levofloxacin is a synthetic molecule with an asymmetric carbon atom in its heterocycle. It is synthesized by reacting chloroform with 2-fluoro-5-nitrobenzaldehyde, which reacts further with sodium hydroxide and hydrochloric acid to form the levofloxacin carboxylic acid. Impurities can be found in the reaction product due to chlorine atoms that are formed during the synthesis. The amount of impurities present in the final product can be determined using a titration method or through HPLC analysis. Levofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.
Fórmula:C13H9F2NO4Pureza:Min. 95%Forma y color:PowderPeso molecular:281.21 g/mol
![(3S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid](https://static.cymitquimica.com/products/IN/thumb/DA0003DO.jpg)
![(S)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid](https://static.cymitquimica.com/products/86/thumb/MM0846.01-0025.jpg)
![(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid](https://static.cymitquimica.com/products/10/thumb/F222352.jpg)
