CAS 102029-49-2

(ile7)-acetato de angiotensina iii

Fórmula: C₄₃H₆₈N₁₂O₉

InChI: InChI=1S/C43H68N12O9/c1-7-24(5)34(40(61)51-31(20-27-21-47-22-49-27)41(62)55-18-10-12-32(55)38(59)54-35(42(63)64)25(6)8-2)53-37(58)30(19-26-13-15-28(56)16-14-26)50-39(60)33(23(3)4)52-36(57)29(44)11-9-17-48-43(45)46/h13-16,21-25,29-35,56H,7-12,17-20,44H2,1-6H3,(H,47,49)(H,50,60)(H,51,61)(H,52,57)(H,53,58)(H,54,59)(H,63,64)(H4,45,46,48)/t24-,25-,29-,30-,31-,32-,33-,34-,35-/m0/s1

Clave InChI: MOLXDYACMRLMMF-GIBVOHFOSA-N

SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H]([C@@H](C)CC)C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)N

[Ile7]-Angiotensin III

CAS: 102029-49-2

Fórmula: C₄₅H₇₄N₁₂O₁₂

Pureza: 98%

Peso molecular: 975.1423

Ref: IN-DA01UOP8

Des-Asp1-[Ile8]-Angiotensin II

CAS: 102029-49-2

Des-Asp1-[Ile8]-Angiotensin II is a peptide that has been shown to have analgesic effects. It has been reported to be active in anesthetized, Sprague-Dawley rats and in primary cultures of rat brain neurons. The peptide binds to the angiotensin II type 1 receptor (AT1) subtype and enhances the activity of the receptor when it is bound by angiotensin II. Des-Asp1-[Ile8]-Angiotensin II also inhibits aminopeptidase activity, leading to an increase in the concentration of angiotensin II. This leads to increased antinociception at high concentrations, which may be due to its effect on baroreceptors or mesenteric blood vessels.

Fórmula: C₄₃H₆₈N₁₂O₉•2CH₃COOH•4H₂O

Pureza: Min. 95%

Peso molecular: 1,089.24 g/mol

Ref: 3D-PAN-4037