CAS 10246-75-0

hidroxizina pamoato

Descripción:

hidroxizina pamoato es un medicamento que se utiliza principalmente por sus propiedades antihistamínicas y ansiolíticas. Es una forma salina de hidroxicina, que es un antihistamínico que puede aliviar los síntomas de alergias, ansiedad y náuseas. La sal pamoato mejora su solubilidad y biodisponibilidad. hidroxizina pamoato se administra típicamente por vía oral y es conocido por sus efectos sedantes, lo que lo hace útil en el tratamiento de trastornos de ansiedad y como premedicación para procedimientos quirúrgicos. El compuesto presenta un peso molecular relativamente alto y se caracteriza por su capacidad para cruzar la barrera hematoencefálica, contribuyendo a sus efectos en el sistema nervioso central. Es importante tener en cuenta que hidroxizina pamoato puede causar efectos secundarios como somnolencia, boca seca y mareos. Al igual que con cualquier medicamento, debe usarse bajo la guía de un profesional de la salud, considerando las posibles interacciones con otros medicamentos y los factores individuales del paciente.

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

InChI: InChI=1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2

Clave InChI: InChIKey=ASDOKGIIKXGMNB-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=C(C(O)=O)C1O)C=CC=C2)C=3C4=C(C=C(C(O)=O)C3O)C=CC=C4.C(N1CCN(CCOCCO)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinónimos:

• 1-(p-Chloro-α-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine, pamoate
• 2-(2-(4-((4-Chlorophenyl)(Phenyl)Methyl)Piperazin-1-Yl)Ethoxy)Ethanol 4,4′-Methylenebis(3-Hydroxy-2-Naphthoate)
• 2-(2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Ethanol
• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol (1:1)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 2-[2-[4-(p-chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol (1:1)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, hydroxyzine salt
• 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylic Acid) - 2-(2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Ethanol (1:1)
• Atarax P
• Equipose
• Ethanol, 2-[2-[4-(p-chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]-, 4,4′-methylenebis[3-hydroxy-2-naphthoate] (1:1) (salt)
• Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (1:1)
• Hydroxyzine Embonate
• Hydroxyzyne pamoate
• Masmoran
• Paxisitil
• Paxistil
• Vistaril

Hydroxyzine Pamoate

CAS: 10246-75-0

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₂₁H₂₇ClN₂O₂·C₂₃H₁₆O₆

Forma y color: Light Yellow Powder

Peso molecular: 374.17611

Ref: 45-1334006

Hydroxyzine Pamoate

CAS: 10246-75-0

Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria and histamine-mediated pruritus.

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: 99.49%

Forma y color: Solid

Peso molecular: 763.274

Ref: TM-T0053

Hydroxyzine Pamoate

CAS: 10246-75-0

Hydroxyzine Pamoate

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: ≥98%

Peso molecular: 763.27

Ref: 54-BUP15032

Hydroxyzine pamoate

CAS: 10246-75-0

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: 98%

Forma y color: Solid

Peso molecular: 763.2738

Ref: IN-DA007FBV

Hydroxyzine Pamoate

Producto controlado

CAS: 10246-75-0

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Forma y color: Neat

Peso molecular: 763.27

Ref: 86-MM3107.00

Hydroxyzine Pamoate

CAS: 10246-75-0

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Forma y color: Neat

Peso molecular: 763.27

Ref: 61-FOR3107.00

Hydroxyzine pamoate

Producto controlado

CAS: 10246-75-0

Hydroxyzine pamoate is a drug that belongs to the group of H1 antagonists. It is used for the treatment of allergic reactions, bowel disease, and infectious diseases. Hydroxyzine pamoate has been shown to have a low potency in animals and humans, with a high incidence of side effects. This drug may act by competing with histamine at the receptor sites on mast cells or basophils. The matrix effect of this drug is unclear. Hydroxyzine pamoate has been shown to inhibit protein synthesis in some bacteria and can be used as an analytical method for detecting histamine in human blood samples.

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: Min. 95%

Forma y color: White To Light (Or Pale) Yellow Solid

Peso molecular: 763.27 g/mol

Ref: 3D-FH171674

Hydroxyzine Pamoate

CAS: 10246-75-0

Applications Hydroxyzine Pamoate is an H1 receptor antagonist. Anxiolytic. Antihistaminic.
References De Bruyn, T. et al.: Mol. Pharm., 83, 1257 (2013); Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Tsau, J., et al.: Anal. Profiles Drug Subs., 7, 319 (1978)

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Forma y color: Neat

Peso molecular: 763.27

Ref: TR-H996505

Hydroxyzine Pamoate

CAS: 10246-75-0

Fórmula: C₂₁H₂₇ClN₂O₂C₂₃H₁₆O₆

Peso molecular: 374.9 : 388.4

Ref: ST-EA-CP-H11010