CAS 1028332-91-3

Fórmula: C21H27N7O

InChI: InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)25-21-26-19-18(22-14-23-19)20(27-21)24-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27)

Clave InChI: GCURSAGINSDQNR-UHFFFAOYSA-N

SMILES: C1CCC(CC1)NC2=NC3=C(C(=N2)NC4=CC=C(C=C4)N5CCOCC5)NC=N3

Retreversine

CAS: 1028332-91-3

Retreversine serves as an inactive control counterpart to Reversine, a pioneering class of ATP-competitive Aurora kinase inhibitor.

Fórmula: C₂₁H₂₇N₇O

Forma y color: Solid

Peso molecular: 393.49

Ref: TM-T73800

Retreversine

CAS: 1028332-91-3

Retreversine is an anticancer drug that belongs to the class of kinase inhibitors. It inhibits the activity of kinases, which are enzymes that regulate various cellular processes such as cell growth, division, and apoptosis. Retreversine has been shown to be effective against a variety of human cancers and cancer cell lines in vitro. It is an analog of indirubin, a natural protein kinase inhibitor found in Chinese urine. Retreversine induces apoptosis in cancer cells by activating caspase-3 and downregulating anti-apoptotic proteins. This drug also has potential as a tumor suppressor due to its ability to inhibit angiogenesis and metastasis.

Fórmula: C₂₁H₂₇N₇O

Pureza: Min. 95%

Peso molecular: 393.5 g/mol

Ref: 3D-DRB33291