CAS 1033719-36-6

Fórmula: C18H20ClNOS

InChI: InChI=1S/C18H19NOS.ClH/c1-19-11-10-15(17-7-4-12-21-17)16-9-8-13-5-2-3-6-14(13)18(16)20;/h2-9,12,15,19-20H,10-11H2,1H3;1H

Clave InChI: AOVAITWXSAKYGE-UHFFFAOYSA-N

SMILES: CNCCC(C1=C(C2=CC=CC=C2C=C1)O)C3=CC=CS3.Cl

Duloxetine EP Impurity E

CAS: 1033719-36-6

Fórmula: C₁₈H₁₉NOSHCl

Peso molecular: 297.42 : 36.46

Ref: ST-EA-CP-D29005

2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol Hydrochloride

Producto controlado

CAS: 1033719-36-6

Impurity Duloxetine EP Impurity E
Stability Hygroscopic
Applications 2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol (Duloxetine EP Impurity E) is an impurity of Duloxetine (D721000), a dual serotonin and norepinephrine reuptake inhibitor (SNRI) used in treatment of stress urinary incontinence.
References Arava, V.R., et al.: Ind. J. Chem. Org. Chem. Med. Chem., 46, 1695 (2007); Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

Fórmula: C₁₈H₁₉NOS•HCl

Forma y color: Neat

Peso molecular: 297.423646

Ref: TR-M287210