CAS 1088-11-5
:2H-1,4-benzodiazepin-2-ona, 7-cloro-1,3-dihidro-5-fenil-
Descripción:
2H-1,4-benzodiazepin-2-ona, 7-cloro-1,3-dihidro-5-fenil- es un compuesto químico que pertenece a la clase de las benzodiazepinas, caracterizado por sus anillos fusionados de benceno y diazepina. Este compuesto típicamente exhibe propiedades como efectos sedantes, ansiolíticos y relajantes musculares, lo que lo hace relevante en farmacología. La presencia de un átomo de cloro en la posición 7 y un grupo fenilo en la posición 5 contribuye a su reactividad química única y actividad biológica. A menudo se estudia por sus posibles aplicaciones terapéuticas, particularmente en el tratamiento de la ansiedad y los trastornos del sueño. La estructura del compuesto permite interacciones con el sistema nervioso central, principalmente a través de la modulación de los receptores GABA, que son cruciales para la neurotransmisión inhibitoria. Además, su solubilidad y estabilidad pueden variar según las condiciones ambientales, influyendo en su biodisponibilidad y eficacia. Las precauciones de seguridad y manejo son esenciales debido a sus propiedades farmacológicas, y está sujeto a controles regulatorios en muchas jurisdicciones.
Fórmula:C15H11ClN2O
InChI:InChI=1/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
Clave InChI:InChIKey=AKPLHCDWDRPJGD-UHFFFAOYSA-N
SMILES:ClC=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3
Sinónimos:- 1-Demethyldiazepam
- 7-Chloro-1,3-dihydro-1H-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazapin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-one
- 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-Chloro-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one
- 7-Chloro-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
- 7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
- 7-Chloro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
- 7-Chloro-5-phenyl-2-oxo-1,2-dihydro-1,4-benzodiazepine
- 7-Chloro-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one
- A 101
- Calmday
- Dealkylprazepam
- Demethyldiazepam
- Demoxazepam
- Desalkylprazepam
- Desmethyldiazepam
- Dmdz
- Madar
- N-Demethyldiazepam
- N-Deoxydemoxepam
- N-Descyclopropylmethylprazepam
- N-Desmethyldiazepam
- N1-Desmethyldiazepam
- N<sup>1</sup>-Desmethyldiazepam
- Nordaz
- Nordazepam
- Nordiazepam
- Norprazepam
- Nsc 46078
- Nsc 631619
- Praxadium
- Ro 5-2180
- Sigma D 7282
- Stilny
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-
- DIAZEPAM, DESMETHYL (RO 5-2180, NORDIAZE P
- 7-Chloro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
- N-Deoxydemoxapam
- 1,4-BENZODIAZEPIN-2-ONE,7-CHLORO-1,3-DIHYDRO-5-PHENYL-
- NDD
- Nordiazepam solution
- Nordazepam CIV (50 mg) (7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one)
- Methanol (test Nordiazepam,1.0mg/mL)
- Ro 52180434
- Chlordesmethyldiazepam
- 7-Chloro-1,3-dihydro-5-phenyl-
- Clorazepate (break down)
- 1,3-Dihydro-7-Chloro-5-Phenyl-2H-1
- DESMETHYLDIAZEPAM METHANOL SOLUTION
- Diazepam EP impurity A
- Desmethyldiazepam solution
- 1,3-Dihydro-7-Chloro-5-Phenyl-2H-1,4-Benzodiazepine-2-One
- DESMETHYLDIAZEPAM--DEA SCHEDULE IV ITEM
- NDZ
- 7-chloro-1,3-dihydro-5-phenyl-2h-4-benzodiazepin-2-one
- Ver más sinónimos
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Encontrado 12 productos.
Desmethyldiazepam (Nordazepam), 1mg/ml in Methanol
CAS:Producto controladoForma y color:Single SolutionNordiazepam-d5 (phenyl-d5)
CAS:Producto controladoPureza:99 atom % DForma y color:White SolidPeso molecular:275.757-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (Nordazepam)
CAS:Producto controladoForma y color:NeatNordazepam
CAS:Producto controlado<p>Applications The primary metabolite of Diazepam. A ligand for the GABAA receptor benzodiazepine modulatory site. Anxiolytic.Controlled substance (depressant).<br>References Klotz, U., et al.: Br. J. Clin. Pharmacol., 7, 119 (1979), Konishi, M., et al.: J. Pharm. Sci., 67, 1777 (1978), Andreoli, V., et al.: Arzneim.-Forsch., 27, 436 (1977), Miller, R.P., et al.: Toxicol. Appl. Pharmacol., 25, 453 (1973), Margolis, J., et al.: Drug Metab. Dispos., 31, 606 (2003),<br></p>Fórmula:C15H11ClN2OForma y color:White To Light YellowPeso molecular:270.71Desmethyl diazepam
CAS:Producto controlado<p>Diazepam is a long-acting benzodiazepine drug that is used for the treatment of a variety of conditions, such as anxiety, insomnia, muscle spasms, and alcohol withdrawal. Diazepam has been shown to have anti-convulsant properties. The hydroxyl group on diazepam's side chain is converted to an ester in order to make it more lipid soluble and therefore more readily absorbed by the body. This conversion occurs partially through the action of enzymes found in the liver microsomes of rats and humans. Desmethyldiazepam (DMDZ) is formed from diazepam by the enzyme monoamine oxidase (MAO). DMDZ has similar pharmacological properties to its parent compound but with a shorter duration of action.<br>Maternal blood levels of DMDZ are higher than those found in serum or plasma, which may be due to differences in protein binding between these two compartments.</p>Fórmula:C15H11ClN2OPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:270.71 g/molNordazepam (1.0 mg/mL in Methanol)
CAS:Producto controladoFórmula:C15H11ClN2OForma y color:Single SolutionPeso molecular:270.71Nordazepam CIV (7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one)
CAS:Producto controladoAlprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) onlyFórmula:C15H11ClN2OForma y color:Light Yellow White PowderPeso molecular:270.05599
