CAS 1093100-40-3

Fórmula: C26H19ClN8

InChI: InChI=1S/C26H19ClN8/c1-15-4-9-19-18(10-12-29-24(19)34-17-7-5-16(27)6-8-17)21(15)35-25-20(3-2-11-28-25)22-23-26(32-13-30-22)33-14-31-23/h2-14H,1H3,(H,28,35)(H,29,34)(H,30,31,32,33)

Clave InChI: KKVYYGGCHJGEFJ-UHFFFAOYSA-N

SMILES: CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6

Raf inhibitor 1

CAS: 1093100-40-3

Raf inhibitor 1

Fórmula: C₂₆H₁₉ClN₈

Pureza: ≥98%

Peso molecular: 478.94

Ref: 54-BUP02549

B-Raf inhibitor 1

CAS: 1093100-40-3

B-Raf inhibitor 1

Fórmula: C₂₆H₁₉ClN₈

Pureza: ≥98%

Peso molecular: 478.93566

Ref: 54-BISN0223

Raf inhibitor 1

CAS: 1093100-40-3

B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor.

Fórmula: C₂₆H₁₉ClN₈

Pureza: 99.91%

Forma y color: Solid

Peso molecular: 478.936

Ref: TM-T2074

B-Raf inhibitor 1

CAS: 1093100-40-3

Fórmula: C₂₆H₁₉ClN₈

Pureza: 98.11%

Forma y color: Solid

Peso molecular: 478.9357

Ref: IN-DA008TEN

B-Raf inhibitor 1

CAS: 1093100-40-3

B-Raf inhibitor 1 is a small molecule that binds to the active conformation of B-Raf, inhibiting its kinase activity. The compound was discovered by screening a library of compounds for conformational specificity and found to be selective for the active conformation of B-Raf. This drug has been shown to inhibit cellular proliferation in vitro and in vivo. Molecular modeling studies have shown that this inhibitor has a high binding affinity for the active conformation of B-Raf. Kinase inhibitors are used as cancer therapy because they inhibit cell growth by blocking the enzyme kinase, which is involved in the transmission of signals from outside to inside cells.

Fórmula: C₂₆H₁₉ClN₈

Pureza: Min. 95%

Peso molecular: 478.94 g/mol

Ref: 3D-TTB10040