CAS 112022-83-0

(R)-2-Metil-CBS-oxazaborolidina

Fórmula: C₁₈H₂₀BNO

InChI: InChI=1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1

Clave InChI: InChIKey=VMKAFJQFKBASMU-QGZVFWFLSA-N

SMILES: CB1OC([C@@]2(N1CCC2)[H])(C3=CC=CC=C3)C4=CC=CC=C4

Sinónimos:

• (3AR)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
• (3aR)-1-methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (3aR)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (R)-(+)-2-Methyl-CBS-oxazaborolindine
• (R)-1-Methyl,3,3-Diphenyl-TETRAHYDRO-PYRROLO(1,2-C)(1,3,2)oxazaborole
• (R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c]-[1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-MethylTETRAHYDRO-1H,3H-PYRROLO[1,2-C][1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-MethylTETRAHYDRO-3H-PYRROLO-[1,2-C][1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
• (R)-5,5-Diphenyl-2-Methyl-3,4-PROPANO-1,3,2-oxazaborolidine
• (R)-Me-CBS
• (R)-Me-Corey-Bakshi-Shibata reagent
• (R)-Methyl oxazaborolidine
• (R)-Methyl-CBS
• (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (R-Methyl-Corey-Bakshi-Shibata catalyst
• 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole, tetrahydro-1-methyl-3,3-diphenyl-, (3aR)-
• 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole, tetrahydro-1-methyl-3,3-diphenyl-, (R)-
• ALPHA,ALPHA-Diphenyl-D-PROLINOL METHYLBORONIC ACID CYCL-AMIDE-ESTER

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine

CAS: 112022-83-0

Fórmula: C₁₈H₂₀BNO

Pureza: >97.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 277.17

Ref: 3B-D2130

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (ca. 1mol/L in Toluene)

CAS: 112022-83-0

Fórmula: C₁₈H₂₀BNO

Forma y color: Colorless to Light yellow clear liquid

Peso molecular: 277.17

Ref: 3B-D5911

(R)-2-Methyl-CBS-oxazaborolidine, 1M soln. in toluene

CAS: 112022-83-0

(R)-2-Methyl-CBS-oxazaborolidine is used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of -hydroxy acids, -amino acids, C2 symmetrical ferrocenyl diols, and propargyl alcohols. It is also used in a desymmetrizing reduction leading to (S)-

Fórmula: C₁₈H₂₀BNO

Forma y color: Clear colorless to yellow to orange, Liquid

Peso molecular: 277.17

Ref: 02-L14582

(R)-Methyl oxazaborolidine 1M in toluene

CAS: 112022-83-0

Fórmula: C₂₅H₂₈BNO

Pureza: 95.0%

Forma y color: Liquid, Clear

Peso molecular: 369.32

Ref: 10-F043435

CALLERY™ (R)-Methyl oxazaborolidine, 1M in toluene

CAS: 112022-83-0

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(R)-Methyloxazaborolidine] (R)-CBS Catalyst

Fórmula: C₁₈H₂₀BNO

Forma y color: colorless to amber liq.

Peso molecular: 277.17

Ref: 08-05-1000

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole

CAS: 112022-83-0

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole

Fórmula: C₁₈H₂₀BNO

Pureza: 97%,99.5%ee

Forma y color: Solid

Peso molecular: 277.1685

Ref: 54-OR360007

(R)-1-methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

CAS: 112022-83-0

Fórmula: C₁₈H₂₀BNO

Pureza: 98%

Forma y color: Solid

Peso molecular: 277.1685

Ref: IN-DA00327K

(R)-(+)-2-Methyl-CBS-oxazaborolidine (1 M in Toluene)

Producto controlado

CAS: 112022-83-0

Fórmula: C₁₈H₂₀BNO

Forma y color: Single Solution

Peso molecular: 277.17

Ref: TR-M295200

(R)-(+)-2-Methyl-CBS-oxazaborolidine

CAS: 112022-83-0

(R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Fórmula: C₁₈H₂₀BNO

Pureza: 97% HPLC

Peso molecular: 277.17

Ref: IN-DG17551

(R)-1-methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

CAS: 112022-83-0

Pureza: 98%, ee99%

Peso molecular: 277.1700134

Ref: 10-F862335

(R)-(+)-2-Methyl-CBS-oxazaborolidine

CAS: 112022-83-0

(R)-(+)-2-Methyl-CBS-oxazaborolidine is a dpp-iv inhibitor that is a β-unsaturated ketone. It has been shown to inhibit the enzyme histone lysine demethylase, which may be involved in the regulation of bone mass. This compound also has a pharmacokinetic profile that is characterized by high oral bioavailability, low plasma protein binding, and rapid metabolism by liver enzymes. The reaction mechanism for this compound is based on the formation of an enolate carbanion. (R)-(+)-2-Methyl-CBS-oxazaborolidine can be synthesized with high stereoselectivity and yields from reactions with simple starting materials. This synthetic route also has a number of advantages over other methods: it does not require any protecting groups, it does not use toxic solvents such as dichloromethane or chloroform, and it can be performed in anhydrous conditions

Fórmula: C₁₈H₂₀BNO

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 277.17 g/mol

Ref: 3D-FM163707