CAS 114-33-0

N'-Metilnicotinamida

Descripción:

N'-Metilnicotinamida es un compuesto orgánico que pertenece a la clase de los derivados de nicotinamida. Se caracteriza por la presencia de un grupo metilo unido al átomo de nitrógeno de la estructura de nicotinamida, que se deriva de la niacina (vitamina B3). Este compuesto es típicamente un sólido cristalino blanco a blanco sucio y es soluble en agua y en varios disolventes orgánicos, lo que lo hace versátil para diferentes aplicaciones. N'-Metilnicotinamida es conocido por su papel en los sistemas biológicos, particularmente en el metabolismo celular y como un posible modulador de ciertas actividades enzimáticas. Se ha estudiado por sus propiedades farmacológicas, incluidos efectos antiinflamatorios y neuroprotectores. La estructura molecular del compuesto incluye un anillo de piridina, que contribuye a su reactividad química e interacción con objetivos biológicos. Debido a sus propiedades, N'-Metilnicotinamida es de interés en la química medicinal y puede tener implicaciones en aplicaciones terapéuticas, aunque se necesita más investigación para elucidar completamente sus mecanismos de acción y beneficios potenciales.

Fórmula: C₇H₈N₂O

InChI: InChI=1/C7H8N2O/c1-8-7(10)6-3-2-4-9-5-6/h2-5H,1H3,(H,8,10)

Clave InChI: InChIKey=ZYVXHFWBYUDDBM-UHFFFAOYSA-N

SMILES: C(NC)(=O)C=1C=CC=NC1

Sinónimos:

• 3-(Methylcarbamoyl)pyridine
• 3-(N-Methylcarbamoyl)pyridine
• 3-Pyridinecarboxamide, N-methyl-
• Methylnicotinamide
• N-Methyl-3-pyridinecarboxamide
• N-methylpyridine-3-carboxamide
• NSC 66521
• Nicotinamide, N-methyl-
• Nicotinic acid methylamide
• Sr 4415
• METHYLNICOTINAMIDE, N-
• N-METHYLNICOTINAMIDE
• N'-METHYLNICOTINAMIDE
• 3-Pyridinecarboxamide,N-methyl-(9CI)

N-Methylnicotinamide

CAS: 114-33-0

Fórmula: C₇H₈N₂O

Pureza: >98.0%(GC)(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 136.15

Ref: 3B-M0374

N-Methylnicotinamide

CAS: 114-33-0

Fórmula: C₇H₈N₂O

Pureza: 96%

Forma y color: Solid

Peso molecular: 136.1512

Ref: IN-DA000A9G

N-Methylnicotinamide

CAS: 114-33-0

N-Methylnicotinamide

Fórmula: C₇H₈N₂O

Pureza: ≥98%

Peso molecular: 136.15

Ref: 54-BUP19469

N-Methylnicotinamide

CAS: 114-33-0

N-Methylnicotinamide

Fórmula: C₇H₈N₂O

Pureza: 98%

Forma y color: Solid

Peso molecular: 136.15

Ref: 54-OR1014436

N-Methyl Nicotinamide

CAS: 114-33-0

Fórmula: C₇H₈N₂O

Peso molecular: 136.15

Ref: 4Z-N-133018

N-Methylnicotinamide-2,4,5,6-d4

CAS: 114-33-0

Pureza: 99 atom % D

Forma y color: White To Off-White Solid

Peso molecular: 140.18

Ref: 3U-D7642

N-Methylnicotinamide

CAS: 114-33-0

Forma y color: Neat

Ref: 86-MM0552.06

N-Methylnicotinamide

CAS: 114-33-0

N-Methylnicotinamide, a niacin metabolite, is found in urine and indicates niacin levels; high in liver cirrhosis, also a microbial product.

Fórmula: C₇H₈N₂O

Pureza: 99.44%

Forma y color: White Solid

Peso molecular: 136.1512

Ref: TM-T5233

N-Methylnicotinamide

CAS: 114-33-0

Applications N-Methylnicotinamide is a metabolite of Nicotinamide (N407750), which is a water-soluble vitamin B, incorporated within nicotinamide cofactors such as NADH and NADPH. N-Methylnicotinamide is commonly found in the human urine and is used as a biomarker to study diseases such as liver cirrhosis and type 2 diabetes.
References Pumpo, R., et al.: Am. J. Gastroenterol., 96, 1183 (2001); Sharma, M., et al.: J. Chem. Pharm. Res., 2, 416 (2010); Al-Nadaf, A., et al.: Bioorg. Medi. Chem., 18, 3088 (2010); Connor, S., et al.: Mol. Biosyst., 6, 909 (2010);

Fórmula: C₇H₈N₂O

Forma y color: Neat

Peso molecular: 136.15

Ref: TR-M321170

N-Methylpyridine-3-carboxamide

CAS: 114-33-0

Fórmula: C₇H₈N₂O

Pureza: 96%

Peso molecular: 136.154

Ref: 10-F180107

N-Methylnicotinamide

CAS: 114-33-0

3-(Methylcarbamoyl)pyridine

Fórmula: C₇H₈N₂O

Pureza: 96%

Peso molecular: 136.15

Ref: IN-DG145158

N-Methyl Nicotinamide

CAS: 114-33-0

Fórmula: C₇H₈N₂O

Peso molecular: 136.15

Ref: ST-EA-CP-N8023

N-Methylnicotinamide

CAS: 114-33-0

N-Methylnicotinamide is an experimental drug that is being studied for its ability to treat metabolic disorders, such as fatty-acid oxidation defects. N-Methylnicotinamide is a competitive inhibitor of the enzyme creatine kinase, which is involved in the metabolism of carbohydrates and fats. It has been shown to be effective in vivo in animals as well as in vitro in cell cultures. The compound binds to the active site of creatine kinase, preventing ATP from binding and inhibiting the phosphorylation of ADP. N-Methylnicotinamide has been shown to be effective against animal models of metabolic disorders, including urea cycle disorders and fatty acid oxidation defects. This agent also shows promise for treating human diseases caused by disturbances in mitochondrial function.

Pureza: Min. 95%

Ref: 3D-FM172332