CAS 1140898-87-8

Fórmula: C18H19Cl2N3O

InChI: InChI=1S/C18H18ClN3O.ClH/c1-17(2,23)14-4-3-11-22-15(14)20-21-16(22)18(9-10-18)12-5-7-13(19)8-6-12;/h3-8,11,23H,9-10H2,1-2H3;1H

Clave InChI: MQBBSMNIRWXALO-UHFFFAOYSA-N

SMILES: CC(C)(C1=CC=CN2C1=NN=C2C3(CC3)C4=CC=C(C=C4)Cl)O.Cl

BMS-823778 hydrochloride

CAS: 1140898-87-8

BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half

Fórmula: C₁₈H₁₉Cl₂N₃O

Forma y color: Solid

Peso molecular: 364.27

Ref: TM-T72249

BMS 823778 hydrochloride

CAS: 1140898-87-8

Selective, potent, competitive and reversible inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) with IC50 of 2.3 nM and more than 10000-fold selectivity over the related 11β-HSD-2 isoform. BMS 823778 inhibits conversion of cortisone in cortisol and has applications in the treatment of diabetes type 2 since it can influence the occurrence of insulin resistance.

Fórmula: C₁₈H₁₈ClN₃O·HCl

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 364.27 g/mol

Ref: 3D-BB167807

BMS 823778 Hydrochloride

Producto controlado

CAS: 1140898-87-8

Fórmula: C₁₈H₁₈ClN₃O·ClH

Forma y color: Neat

Peso molecular: 364.269

Ref: TR-B216170