CAS 116-43-8

Succinilsulfatiazol

Descripción:

Succinilsulfatiazol es un antibiótico sulfonamida que se utiliza principalmente por sus propiedades antibacterianas. Se caracteriza por su grupo sulfonamida, que es esencial para su actividad antimicrobiana, y un anillo de tiazol que contribuye a su estabilidad química y solubilidad. El compuesto es típicamente un polvo cristalino blanco a blanco sucio, y es soluble en agua, lo que facilita su uso en diversas formulaciones. Succinilsulfatiazol actúa inhibiendo el crecimiento bacteriano a través de la inhibición competitiva de la enzima dihidropteroato sintasa, que está involucrada en la síntesis de folato. Este mecanismo lo hace efectivo contra una variedad de bacterias Gram-positivas y Gram-negativas. Además, se ha utilizado en el tratamiento de infecciones gastrointestinales debido a su acción localizada en los intestinos. Sin embargo, su uso ha disminuido con la llegada de antibióticos más efectivos y preocupaciones sobre la resistencia. Al igual que con muchas sulfonamidas, los efectos secundarios potenciales pueden incluir reacciones alérgicas y problemas hematológicos, lo que requiere un monitoreo cuidadoso durante el tratamiento.

Fórmula: C₁₃H₁₃N₃O₅S₂

InChI: InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)

Clave InChI: InChIKey=SKVLYVHULOWXTD-UHFFFAOYSA-N

SMILES: S(NC1=NC=CS1)(=O)(=O)C2=CC=C(NC(CCC(O)=O)=O)C=C2

Sinónimos:

• 2-(N⁴-Succinylsulfanilamido)thiazole
• 3-([4-[(1,3-Thiazol-2-yl)sulfamoyl]phenyl]carbamoyl)propanoic acid
• 4-Oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]butanoic acid
• 4-Oxo-4-{[4-(1,3-Thiazol-2-Ylsulfamoyl)Phenyl]Amino}Butanoic Acid
• 4′-(2-Thiazolylsulfamoyl)succinanilic acid
• Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
• Colistatin
• Cremosuxidine
• Kaoxidin
• Kaoxidine
• NSC 14193
• NSC 163939
• Rolsul
• SST
• Succinanilic acid, 4′-(2-thiazolylsulfamoyl)-
• Succinylsulphathiazole
• Sulfadigesin
• Sulfasuccidin
• Sulfasuccidine
• Sulfasuccinil
• Sulfasuccithiazole
• Sulfasuxidine
• Sulfenterone
• Thiacyl

Succinylsulfathiazole

CAS: 116-43-8

Succinylsulfathiazole (Succinylsulphathiazole) is a sulfonamide. An ultra long-acting drug.

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: 98.77%

Forma y color: Solid

Peso molecular: 355.389

Ref: TM-T0749

Succinylsulfathiazole

CAS: 116-43-8

Fórmula: C₁₃H₁₃N₃O₅S₂·xH₂O

Pureza: 99.0 - 101.0 % (dried basis)

Forma y color: White or yellowish-white crystalline powder

Peso molecular: 355.39 (anhydrous)

Ref: 7W-GA4716

Succinylsulfathiazole

CAS: 116-43-8

Succinylsulfathiazole

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: 98.5%

Peso molecular: 355.39

Ref: 54-BUP17048

Succinylsulfathiazole

CAS: 116-43-8

Succinylsulfathiazole

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: >98%

Peso molecular: 355.39

Ref: 54-OR1015091

Succinylsulfathiazole

CAS: 116-43-8

Fórmula: C₁₃H₁₃N₃O₅S₂

Forma y color: Neat

Peso molecular: 355.39

Ref: 04-C16985600

Succinylsulfathiazole

CAS: 116-43-8

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: 99%

Forma y color: Solid

Peso molecular: 355.3894

Ref: IN-DA000BCQ

Succinylsulfathiazole

Producto controlado

CAS: 116-43-8

Applications Succinylsulfathiazole is a sulfonamide antibiotic that was shown to inhibit bacteria that are responsible for folate production. Succinylsulfathiazole was used in various folate deficiency studies to block the synthesis of folic acid.
References Semchuk, G.M., et al.: J. Nutrition., 124, 1118 (1994); Adikrisna, R., et al.: Gastroenterol., 143, 234 (2012); Suihko, E., et al.: J. Pharma. Sci., 94, 745 (2005);

Fórmula: C₁₃H₁₃N₃O₅S₂

Forma y color: Neat

Peso molecular: 355.39

Ref: TR-S692170

succinylsulfathiazole

CAS: 116-43-8

Fórmula: C₁₃H₁₃N₃O₅S₂

Peso molecular: 355.4

Ref: BE-BePure-25619

4-Oxo-4-((4-(N-(thiazol-2-yl)sulfamoyl)phenyl)amino)butanoic acid

CAS: 116-43-8

4-Oxo-4-((4-(N-(thiazol-2-yl)sulfamoyl)phenyl)amino)butanoic acid

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: 98%

Peso molecular: 355.39

Ref: IN-DG152083

Succinylsulfathiazole

CAS: 116-43-8

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: ≥99 %

Peso molecular: 355.38

Ref: 10-F544151

Succinylsulfathiazole

CAS: 116-43-8

Succinylsulfathiazole is a sulfa drug that has antimicrobial activity. It is a structural analogue of sulfanilamide, which is an antibiotic used to treat infectious diseases. Sulfa drugs are structurally related to the amino acid pantothenic acid and have been shown to have beneficial effects in animal models for bowel disease, autoimmune diseases, and other conditions. Succinylsulfathiazole has been shown to inhibit the growth of Aerobacter aerogenes and other bacteria by binding to their cell wall and interfering with synthesis of DNA. Succinylsulfathiazole has been shown to inhibit the growth of Aerobacter aerogenes and other bacteria by binding to their cell wall and interfering with synthesis of DNA.

Fórmula: C₁₃H₁₃N₃O₅S₂

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 355.39 g/mol

Ref: 3D-FS41022