CAS 125700-67-6

O-(Benzotriazol-1-il)-N,N,N′,N′-tetrametiluronio tetrafluoroborato

Descripción:

O-(Benzotriazol-1-il)-N,N,N′,N′-tetrametiluronio tetrafluoroborato, con número CAS 125700-67-6, es un compuesto químico comúnmente utilizado como reactivo de acoplamiento en la síntesis de péptidos y otras reacciones orgánicas. Presenta un grupo de benzotriazole, que mejora su reactividad y estabilidad, haciéndolo efectivo para facilitar la formación de enlaces amida. La presencia del grupo tetrametilurónico contribuye a su capacidad para activar ácidos carboxílicos, promoviendo su conversión en especies más reactivas. Este compuesto es típicamente un sólido blanco a blanco sucio y es soluble en disolventes orgánicos polares. Su contraión tetrafluoroborato proporciona características adicionales de estabilidad y solubilidad. Al igual que con muchos reactivos de acoplamiento, es importante manejar esta sustancia con cuidado, ya que puede representar riesgos para la salud si se inhala o ingiere. Se deben seguir los protocolos de seguridad de laboratorio adecuados al trabajar con este compuesto, incluyendo el uso de equipo de protección personal y métodos apropiados de eliminación de desechos.

Fórmula: C₁₁H₁₆N₅O·BF₄

InChI: InChI=1S/C11H16N5O.BF4/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1

Clave InChI: InChIKey=ZXZJCMUCQIOBGO-UHFFFAOYSA-N

SMILES: C(N(C)C)(N(C)C)=[N+]1C=2C(N(=O)=N1)=CC=CC2.[B+3]([F-])([F-])([F-])[F-]

Sinónimos:

• (Benzotriazol-1-yloxy-dimethylamino-methylene)dimethylammonium tetrafluoroborate
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-)
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1)
• 2-(1H-Benzotriazol-1-YL)-1,1,3,3-tetramethyluronium Tetrafluoroborate
• 2-(1H-Benzotriazol-1-yl)-N,N,N′,N′-tetramethylammonium tetrafluoroborate
• Benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate
• Knorr Reagent
• N,N,N',N'-tetramethyl-O-(Benzotriazol-1-YL)uronium Tetrafluoroborate
• N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium Tetrafluoroborate
• O-(1H-Benzotriazol-1-YL)-1,1,3,3-tetramethyl-uronium Tetrafluoroborate
• O-(1H-Benzotriazol-1-YL)-N,N,N',N'-tetramethyluronium Tetrafluoroborate
• O-(1H-Benzotriazole-1-YL) N,N,N',N'-tetramethyl uronium Tetrafluoroborate
• O-(Benzotriazol-1-yl)-N,N,N',N'-tetra methyluronium Tetrafluoroborate
• O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
• O-(Benzotriazol-l-yl)-N,N,N,N,-tetramethyluronium Tetrafluoroborate
• O-Benzotriazol-1-yl-tetramethyluronium tetrafluoroborate
• O-Benzotriazolyl tetramethylisouronium tetrafluoroborate

TBTU [Coupling Reagent for Peptide]

CAS: 125700-67-6

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 321.09

Ref: 3B-B1658

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%

CAS: 125700-67-6

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate is used as used for solid-phase peptide synthesis. It is also used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides. This Thermo Scientific Chemicals brand p

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: 99%

Forma y color: Crystalline powder or powder, White to cream

Peso molecular: 321.09

Ref: 02-L13470

TBTU

CAS: 125700-67-6

TBTU is successfully used as coupling reagent in solid phase peptide synthesis. It acts as an excellent activating reagent causing low racemization during condensation of peptide segments. A study of the structure of TBTU in solid state as well as in solution by Abdelmoty et al. showed that the compound is a guanidinium N-oxide and not an uronium salt.

Fórmula: C₁₁H₁₆BF₄N₅O

Forma y color: White

Peso molecular: 321.09

Ref: 01-4013268

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate

Fórmula: C₁₁H₁₆N₅O·BF₄

Pureza: ≥95%

Forma y color: White Solid-Powder

Peso molecular: 321.08224

Ref: 54-PC0921

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: 98%

Forma y color: Solid

Peso molecular: 321.0823

Ref: IN-DA000OI0

TBTU

CAS: 125700-67-6

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: ≥ 99.0%

Forma y color: White to almost white powder

Peso molecular: 321.08

Ref: 7W-GE5057

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: 98.0%

Forma y color: Solid

Peso molecular: 321.09

Ref: 10-F009020

TBTU

CAS: 125700-67-6

1-(Bs(dimethylamino)methylene)-1H-benzo[d][1,2,3]triazole-1-ium 3-oxide tetrafluoroborate

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: 98%

Peso molecular: 321.08

Ref: IN-DG17881

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium Tetrafluoroborate

Producto controlado

CAS: 125700-67-6

Applications O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium Tetrafluoroborate is used in the synthesis of tetrapeptoid analogues of the antiprotocoal compound Apicidin (A726300). Also used in the synthesis of acid based t-antigen glycodendrimers.
References Murray, P. et al.: Bioorg. Med. Chem. Lett., 11, 773 (2001); Roy, R. et al.: J. Am. Chem. Soc., 123, 1809 (2001);

Fórmula: C₁₁H₁₆BF₄N₅O

Forma y color: Neat

Peso molecular: 321.08

Ref: TR-B206995

TBTU

CAS: 125700-67-6

TBTU is an aminium coupling reagent used for amide and ester synthesis. TBTU is a stable, efficient and reactive reagent suitable for solution and solid-phase peptide synthesis. With TBTU high yields, racemisation suppression and fast reaction times are achieved. TBTU contains the carbodiimide and benzotriazole moieties, generates HOBt and water-soluble by-products. TBTU can be used in its polymer-bound form as a solid-supported peptide coupling reagent efficient even in presence of water and can be easily separated and regenerated after the reaction. TBTU finds application in the synthesis of biologically active peptides, such as azapeptides.

Fórmula: C₁₁H₁₆N₅O·BF₄

Pureza: Min. 99 Area-%

Forma y color: White Off-White Powder

Peso molecular: 321.08 g/mol

Ref: 3D-FT07096

TBTU Reagent

CAS: 125700-67-6

TBTU Reagent is a combination of two reagents that are used for peptide synthesis and purification. TBTU is an amide coupling reagent that reacts with the carboxyl group of an ester to form a reactive intermediate, which then reacts with the amino group of an amide. This reaction forms an amide bond between the carboxyl group of the ester and the amino group of the amide. TBTU Reagent has been used in vitro assays to measure pharmacological activities such as anti-inflammatory effects and antimicrobial effects. TBTU Reagent has also been used to prepare mouse monoclonal antibodies against toll-like receptor 4 (TLR4).

Fórmula: C₁₁H₁₆N₅OBF₄

Pureza: Min. 95%

Peso molecular: 321.08 g/mol

Ref: 3D-KTB-1066-PI

TBTU extrapure, 98%

CAS: 125700-67-6

Fórmula: C₁₁H₁₆BF₄N₅O

Pureza: min. 98%

Forma y color: White, Crystalline powder

Peso molecular: 321.08

Ref: SR-47064

O-(Benzotriazol-1-yl)-N,N,N’,N’-Tetramethyluronium Tetrafluoroborate

CAS: 125700-67-6

Fórmula: C₁₁H₁₆N₅OBF₄

Peso molecular: 234.28 : 86.80

Ref: ST-EA-CP-CS5328

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

Please enquire for more information about O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₁₁H₁₆BF₄N₅O

Peso molecular: 321.08 g/mol

Ref: 3D-J-523817