
CAS 1261393-15-0
:Fórmula:C25H25N5O4
InChI:InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)/i1+1D3
Clave InChI:QNZCBYKSOIHPEH-KQORAOOSSA-N
SMILES:[2H][13C]([2H])([2H])OC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
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Apixaban-13C-d3
CAS:Fórmula:C2413CH22D3N5O4Forma y color:White To Off-White SolidPeso molecular:463.52Apixaban 13C,D3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFórmula:C25H25N5O4Pureza:98%Forma y color:White SolidPeso molecular:463.5082Apixaban-13C, d3
CAS:Producto controladoApplications Apixaban-13C, d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);Fórmula:C2413CH22D3N5O4Forma y color:NeatPeso molecular:463.51Apixaban-13C, d3
CAS:Producto controladoApixaban-13C, d3 is a chromatographic and spectrometric standard that is used in the linkage of pharmaceuticals. It is a bioavailable inhibitor that prevents coagulation by inhibiting the activity of thrombin. Apixaban-13C, d3 has a low level of toxicity and can be administered orally or intravenously. The pharmacokinetic profile for this compound has been determined using ammonium formate as an internal standard. Calibration was performed using mass spectrometry to confirm the molecular weight at 274.2 amu.Fórmula:C25H22D3N5O4Pureza:Min. 95%Peso molecular:463.51 g/mol







