CAS 128-13-2

Ácido ursodesoxicólico

Descripción:

Ácido ursodesoxicólico (UDCA), con el número CAS 128-13-2, es un ácido biliar que se encuentra de forma natural en el cuerpo, sintetizado principalmente a partir del colesterol. Se caracteriza por sus propiedades hidrofílicas, que lo hacen menos tóxico que otros ácidos biliares. Se conoce que el UDCA promueve la solubilización del colesterol en la bilis, ayudando así a prevenir la formación de cálculos biliares de colesterol. Se ha utilizado terapéuticamente para tratar diversas enfermedades hepáticas, incluyendo la colangitis biliar primaria y ciertas formas de colestasis. El compuesto exhibe una estructura única, con un grupo hidroxilo en la posición 7, lo que contribuye a su solubilidad y actividad biológica. Además, el UDCA tiene efectos antiinflamatorios e inmunomoduladores, lo que lo hace beneficioso en el manejo de condiciones relacionadas con el hígado. Su mecanismo de acción implica mejorar el flujo biliar y reducir la toxicidad de los ácidos biliares, lo que puede ser particularmente ventajoso en la disfunción hepática. En general, Ácido ursodesoxicólico es un compuesto significativo tanto en contextos clínicos como bioquímicos, reflejando su importancia en la salud gastrointestinal y el manejo de enfermedades.

Fórmula: C₂₄H₄₀O₄

InChI: InChI=1/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15-,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1

Clave InChI: InChIKey=RUDATBOHQWOJDD-UZVSRGJWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Sinónimos:

• (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid
• 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol
• 3α,7β-Dihydroxy-5β-cholan-24-oate
• 3α,7β-Dihydroxy-5β-cholan-24-oic acid
• 3α,7β-Dihydroxy-5β-cholanic acid
• 3α,7β-Dihydroxy-5β-cholanoic acid
• 3α,7β-Dihydroxycholanic acid
• 5β-Cholan-24-oic acid, 3α,7β-dihydroxy-
• 5β-Cholanic acid, 3α,7β-dihydroxy-
• 7β-Hydroxylithocholic acid
• Acide Ursodesoxycholique
• Acido Ursodeoxicolico
• Actigall
• Adursal
• Arsacol
• CHOLON-24-OIC ACID, 3,7-DIHYDROXY-(3α, 5β, 7.β)-
• Cholit-Ursan
• Delursan
• Desocol
• Desol
• Destolit
• Deursil
• Litursol
• Lyeton
• Nsc 683769
• Paptarom
• Solutrat
• Udca
• Urdes
• Urosiol
• Ursacol
• Ursic acid
• Urso
• Ursobilin
• Ursochol
• Ursocholic acid, deoxy-
• Ursocol
• Ursodamor
• Ursodeoxycholic Acid
• Ursodeoxycholsaure
• Ursodesoxycholic acid
• Ursodiol
• Ursofalk
• Ursogall
• Ursolvan
• Ursosan
• (4R)-4-[(3R,5S,7S,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol
• (4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5alpha,7beta)-3,7-dihydroxycholan-24-oate
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oate
• 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid
• (3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxycholan-24-oic acid
• Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-
• (3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
• 3,7-Dihydroxycholan-24-oic acid
• 5BETA-CHOLANIC ACID-3ALPHA,7BETA-DIOL
• 3,7-dihydroxy-,(3-alpha,5-beta,7-beta)-cholan-24-oicaci
• 17-beta-(1-methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diol
• 3ALPHA, 7BETA-DIOXYCHOLANIC ACID
• 5BETA-CHOLAN-24-OIC ACID-3ALPHA, 7BETA-DIOL
• (6-BETA)-CHOLANIC ACID-(3-ALPHA)-(7-BETA)-DIOL
• UDCS
• 6BETA-CHOLANIC ACID-3A,7BETA-DIOL
• 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLANIC ACID
• 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID
• 7BETA-HYDROXYLITHOCHOLIC ACID
• 3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oicaci

Ursodeoxycholic acid

Producto controlado

CAS: 128-13-2

Ursodeoxycholic acid is a secondary bile acid, which is derived from the metabolism of primary bile acids by intestinal bacteria. It modifies the composition of bile and reduces the absorption of cholesterol in the gastrointestinal tract by decreasing the cholesterol saturation of bile. This leads to a solubilization of cholesterol gallstones, making it an essential therapeutic agent in the management of cholesterol gallstone disease.

Fórmula: C₂₄H₄₀O₄

Forma y color: Powder

Peso molecular: 392.57 g/mol

Ref: 3D-FU09676

Ursodeoxycholic acid

Producto controlado

CAS: 128-13-2

Ursodeoxycholic acid is a naturally occurring bile acid, which is synthesized in the liver from cholesterol. It functions primarily to reduce cholesterol absorption in the intestine and dissolve cholesterol gallstones. This mechanism involves changing the composition of bile and reducing the cholesterol saturation in bile, which reduces micellar cholesterol and bile acid pool size, limiting stone formation.

Fórmula: C₂₄H₄₀O₄

Pureza: Min. 98 Area-%

Peso molecular: 392.58 g/mol

Ref: 3D-U-9000

Ursodeoxycholic acid

CAS: 128-13-2

Ref: BE-RMT20080-1G

Ursodeocycholic Acid-3-Sulfate Sodium Salt

CAS: 128-13-2

Ref: BE-MU-1038

Ursodeoxycholic acid

CAS: 128-13-2

Ref: BE-RMT20080

Ursodeoxycholic Acid-[13C3] in Methanol

CAS: 128-13-2

Methanol

Ref: BE-MC-1006XM-100

Ursodeoxycholic Acid in Methanol

CAS: 128-13-2

Methanol

Ref: BE-MU-1006YM-1000

Ursodeoxycholic Acid

CAS: 128-13-2

(R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Fórmula: C₂₄H₄₀O₄

Pureza: 98%

Peso molecular: 392.57

Ref: IN-DG17928

Ursodeoxycholic Acid (UDCS) extrapure, 99%

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Pureza: min. 99.5%

Forma y color: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecular: 392.57

Ref: SR-50178