CAS 128-53-0
:N-etilmaleimida
Descripción:
N-etilmaleimida es un compuesto orgánico caracterizado por su estructura de maleimida, que presenta un anillo de cinco miembros que contiene un grupo carbonilo y un átomo de nitrógeno. Es un líquido incoloro a amarillo pálido a temperatura ambiente, exhibiendo un olor distintivo. Este compuesto es conocido por su reactividad, particularmente en la formación de enlaces covalentes con nucleófilos, lo que lo convierte en un reactivo valioso en la síntesis orgánica y la bioquímica. N-etilmaleimida se utiliza a menudo en la modificación de proteínas y péptidos, ya que puede reaccionar selectivamente con grupos tiol, facilitando el estudio de la estructura y función de las proteínas. Además, se utiliza en la producción de polímeros y como agente de entrecruzamiento en varios procesos químicos. El compuesto es soluble en disolventes orgánicos como acetona y etanol, pero tiene una solubilidad limitada en agua. Se deben tomar precauciones de seguridad al manipular N-etilmaleimida, ya que puede ser irritante para la piel y los ojos, y son necesarias condiciones de almacenamiento adecuadas para mantener su estabilidad.
Fórmula:C6H7NO2
InChI:InChI=1/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
Clave InChI:InChIKey=HDFGOPSGAURCEO-UHFFFAOYSA-N
SMILES:C(C)N1C(=O)C=CC1=O
Sinónimos:- 1-Ethyl-1H-pyrrole-2,5-dione
- 1-Ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
- Ethylmaleimide
- Maleic acid N-ethylimide
- Maleimide, N-ethyl-
- N-Ethylmaleimid
- N-Ethylmaleimide
- N-etilmaleimida
- NEM
- Nsc 7638
- 1H-Pyrrole-2,5-dione, 1-ethyl-
- N-Ethylmaleimide, (NEM)
- 1-Ethyl-1H-pyrrole-2,5-dione~NEM
- ethvlmaleimide
- 1-ethyl-1h-pyrrole-5-dione
- USAF B-121
- maleicacidn-ethylimide
- N-ETHYLMALEIMIDE SIGMAULTRA
- N-ETHYLMALEIMIDE 99+%
- n-ethvlmaleimide
- n-ethyl-maleimid
- 5-dione,1-ethyl-1H-Pyrrole-2
- N-Ethylmaleimide-D5
- usafb-121
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N-Ethylmaleimide
CAS:Fórmula:C6H7NO2Pureza:>98.0%(HPLC)(N)Forma y color:White powder to crystalPeso molecular:125.13N-Ethylmaleimide, 98+%
CAS:Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peFórmula:C6H7NO2Pureza:98+%Forma y color:White to cream or pale yellow, Crystals or powder or crystalline powder and/or lumps/chunks or fused solidPeso molecular:125.13N-Ethylmaleimide, 99+%
CAS:N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a MichaFórmula:C6H7NO2Pureza:99+%Forma y color:White to pale cream, Crystals or powder or crystalline powder and/or chunksPeso molecular:125.13N-Ethylmaleimide
CAS:N-EthylmaleimideFórmula:C6H7NO2Pureza:98%Forma y color:SolidPeso molecular:125.13N-Ethylmaleimide
CAS:Fórmula:C6H7NO2Pureza:(GC) ≥ 98.0%Forma y color:White to light-yellow crystalline powderPeso molecular:125.13N-Ethyl Maleimide
CAS:Producto controladoApplications Reagent for the covalent modification of cysteine residues in proteins.NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sheehan, M., et al.: J. Cell Biol., 106, 1 (1988), Vogel, K., et al.: J. Biol. Chem., 275, 2959 (2000), Ramos, C., et al.: Biochem. J., 400, 393 (2006),Fórmula:C6H7NO2Forma y color:NeatPeso molecular:125.13N-Ethylmaleimide
CAS:N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.Fórmula:C6H7NO2Pureza:99.91% - 99.95%Forma y color:White SolidPeso molecular:125.12531-Ethyl-1H-pyrrole-2,5-dione
CAS:1-Ethyl-1H-pyrrole-2,5-dioneFórmula:C6H7NO2Pureza:97%Peso molecular:125.13N-Ethyl maleimide
CAS:N-Ethyl maleimide is a cytosolic calcium chelator that binds to the calcium ions in the cells. It has been shown to inhibit the enzymes of fatty acid synthesis and phospholipase A2, which are involved in lipid metabolism. N-Ethyl maleimide is an irreversible enzyme inhibitor and can be used as a chemical tool for cell sample preparation. The reaction with N-ethyl maleimide leads to a decrease in water permeability of the cell membrane. This chemical also has a high affinity for sulfhydryl groups and can therefore be used as an anti-oxidant or free radical scavenger.Fórmula:C6H7NO2Pureza:Min. 95%Forma y color:PowderPeso molecular:125.13 g/molN-Ethyl Maleimide (1M Solution in Acetonitrile)
CAS:Producto controladoFórmula:C6H7NO2Forma y color:Single SolutionPeso molecular:125.13N-Ethylmaleimide ExiPlus, Multi-Compendial, 99%
CAS:Fórmula:C6H7NO2Pureza:min. 99%Forma y color:White to Pale yellow, Crystalline powder / Crystals, Clear, Colourless to pale yellowPeso molecular:125.13N-Ethylmaleimide extrapure, 99%
CAS:Fórmula:C6H7NO2Pureza:min. 99%Forma y color:White to off-white to pale yellow, Crystalline powder / CrystalsPeso molecular:125.13
