CAS 128517-07-7

(1S,4Z,7S,10S,11E,20R)-4-etilideno-7,20-dipropan-2-il-9-oxa-15,16-ditia-3,6,18,21-tetrazabiciclo[8.7.6]tricos-11-eno-2,5,8,19,22-pentona

Descripción:

La sustancia química con el nombre "(1S,4Z,7S,10S,11E,20R)-4-etilideno-7,20-dipropan-2-il-9-oxa-15,16-ditia-3,6,18,21-tetrazabiciclo[8.7.6]tricos-11-eno-2,5,8,19,22-pentona" y número CAS "128517-07-7" es un compuesto orgánico complejo caracterizado por su estructura bicíclica única, que incorpora múltiples grupos funcionales, incluidos los moieties oxo y thia. La estereoquímica indicada por las designaciones (S) y (Z) sugiere arreglos espaciales específicos de átomos, que pueden influir significativamente en la reactividad e interacciones del compuesto. La presencia de múltiples grupos alquilo, como etilideno y dipropan-2-il, contribuye a sus características hidrofóbicas, mientras que el marco bicíclico puede impartir rigidez a la molécula. Este compuesto probablemente exhiba propiedades químicas interesantes, incluida una posible actividad biológica, debido a su intrincada estructura. Sus aplicaciones podrían abarcar varios campos, incluidos los farmacéuticos y la ciencia de materiales, aunque los usos específicos dependerían de una investigación adicional sobre sus propiedades y comportamiento en diferentes entornos.

Fórmula: C₂₄H₃₆N₄O₆S₂

InChI: InChI=1/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17+,19+,20-/m0/s1

Clave InChI: OHRURASPPZQGQM-GCCNXGTGSA-N

SMILES: C/C=C\1/C(=O)N[C@H](C(=O)O[C@H]\2CC(=O)N[C@@H](C(=O)N[C@H](CSSCC/C=C2)C(=O)N1)C(C)C)C(C)C

Sinónimos:

• Fr 901228
• Romidepsin
• (1R,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone

Romidepsin

CAS: 128517-07-7

Romidepsin

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: ≥98%

Peso molecular: 540.7

Ref: 54-BUP04661

Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3→5)-disulfide

CAS: 128517-07-7

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 540.6958

Ref: IN-DA000Y5C

Romidepsin

Producto controlado

CAS: 128517-07-7

Applications Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),

Fórmula: C₂₄H₃₆N₄O₆S₂

Forma y color: Neat

Peso molecular: 540.7

Ref: TR-R425060

Romidepsin

CAS: 128517-07-7

Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: 99.4% - 99.99%

Forma y color: Solid

Peso molecular: 540.7

Ref: TM-T6006

Romidepsin

CAS: 128517-07-7

Fórmula: C₂₄H₃₆N₄O₆S₂

Peso molecular: 540.69

Ref: 4Z-R-160001

Romidepsin

CAS: 128517-07-7

(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentaone

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: 99%

Peso molecular: 540.7

Ref: IN-DG243733

Romidepsin

CAS: 128517-07-7

Natural anti-cancer agent; inhibitor of histone deacetylases

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: Min. 95 Area-%

Forma y color: White Powder

Peso molecular: 540.7 g/mol

Ref: 3D-FR10656

Romidepsin - Bio-X ™

CAS: 128517-07-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 540.7 g/mol

Ref: 3D-BR300116

Romidepsin

CAS: 128517-07-7

Fórmula: C₂₄H₃₆N₄O₆S₂

Peso molecular: 540.7

Ref: BE-RMCR110000

Romidepsin

CAS: 128517-07-7

Pureza: 98%

Peso molecular: 540.69

Ref: 10-F979349

Romidepsin-d8

Producto controlado

CAS: 128517-07-7

Applications Labelled Romidepsin (R425060). Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),

Fórmula: C₂₄D₈H₂₈N₄O₆S₂

Forma y color: Neat

Peso molecular: 548.745

Ref: TR-R425062

Romidepsin

CAS: 128517-07-7

Fórmula: C₂₄H₃₆N₄O₆S₂

Peso molecular: 540.7

Ref: ST-EA-CP-R56000