
CAS 1332391-11-3
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Encontrado 9 productos.
N-Desmethyl-Apalutamide
CAS:N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.Fórmula:C20H13F4N5O2SPureza:98.6%Forma y color:SolidPeso molecular:463.41Ref: TM-T12146
1mg117,00€5mg259,00€10mg374,00€25mg562,00€50mg775,00€100mg1.035,00€200mg1.406,00€1mL*10mM (DMSO)279,00€N-Desmethyl Apalutamide
CAS:Fórmula:C20H13F4N5O2SForma y color:White To Off-White SolidPeso molecular:463.41N-Desmethyl Apalutamide D-13C215N
CAS:Producto controladoFórmula:C2C18H13F415NN4O2SForma y color:NeatPeso molecular:466.387N-Desmethyl Apalutamide-d4
CAS:Producto controladoFórmula:C20D4H9F4N5O2SForma y color:NeatPeso molecular:467.433N-Desmethyl Apalutamide
CAS:Producto controladoApplications N-Desmethyl Apalutamide has been exploresd asthiohydantion androgen receptor antagonist for treament of cancer
References Bignan, G.C. PCT Int. Appl. (2018), WO 2018037342 A1 20180301.Fórmula:C20H13F4N5O2SForma y color:NeatPeso molecular:463.41N-Desmethyl-apalutamide
CAS:Apalutamide is a nonsteroidal antiandrogen that binds to the androgen receptor in prostate cancer cells. It has been shown to inhibit the proliferation of human prostate cancer cell lines and tumor xenografts in nude mice. Apalutamide is a potent inhibitor of protein interactions with the androgen receptor, which may be due to its ability to compete with testosterone for binding sites. It also has an activating effect on the androgen receptor, leading to increased transcription of genes regulated by this receptor.
Fórmula:C20H13F4N5O2SPureza:Min. 95%Peso molecular:463.4 g/mol






