CAS 1351669-68-5

Fórmula: C22H43NO4S

InChI: InChI=1S/C22H43NO4S/c1-4-5-6-7-8-9-10-11-15-20-21(27-22(20)24)16-12-13-18-28(25,26)19-14-17-23(2)3/h20-21H,4-19H2,1-3H3/t20-,21-/m0/s1

Clave InChI: HVJGVPUJTPBPAM-SFTDATJTSA-N

SMILES: CCCCCCCCCC[C@H]1[C@@H](OC1=O)CCCCS(=O)(=O)CCCN(C)C

Palmostatin M

CAS: 1351669-68-5

Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) within cells, with an IC₅₀ of 2.5 nM for APT1. It disrupts the depalmitoylation cycle of Ras, thus downregulating the overall Ras signaling pathway. Palmostatin M is applicable in cancer research.

Fórmula: C₂₂H₄₃NO₄S

Peso molecular: 417.65

Ref: TM-T219042