CAS 1351758-81-0

Fórmula: C17H20ClN5O3

InChI: InChI=1S/C17H20ClN5O3/c1-19-15-12(18)10-20-17(22-15)21-13-4-3-11(9-14(13)25-2)16(24)23-5-7-26-8-6-23/h3-4,9-10H,5-8H2,1-2H3,(H2,19,20,21,22)

Clave InChI: YEVOZZZLKJKCCD-UHFFFAOYSA-N

SMILES: CNC1=NC(=NC=C1Cl)NC2=C(C=C(C=C2)C(=O)N3CCOCC3)OC

HG-10-102-01

CAS: 1351758-81-0

HG-10-102-01

Fórmula: C₁₇H₂₀ClN₅O₃

Pureza: ≥98%

Peso molecular: 377.83

Ref: 54-BUP09848

(4-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-methoxyphenyl)(morpholino)methanone

CAS: 1351758-81-0

Fórmula: C₁₇H₂₀ClN₅O₃

Pureza: 98%

Peso molecular: 377.8254

Ref: IN-DA009CC8

HG-10-102-01

CAS: 1351758-81-0

HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).

Fórmula: C₁₇H₂₀ClN₅O₃

Pureza: 99.59%

Forma y color: Solid

Peso molecular: 377.825

Ref: TM-T7196

[4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone

Producto controlado

CAS: 1351758-81-0

Fórmula: C₁₇H₂₀ClN₅O₃

Forma y color: Neat

Peso molecular: 377.825

Ref: TR-C369030

[4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone

CAS: 1351758-81-0

The drug, AZD1480, is a small molecule that binds to the toll-like receptor TLR4 and inhibits its function. This drug has been shown to inhibit microglia activation and reduce the production of pro-inflammatory cytokines in cell culture studies. The effects of AZD1480 are mediated by inhibiting autophagy, which is a process that cells use to degrade damaged proteins and organelles. This drug also inhibits the activity of polymerase chain reaction (PCR) enzymes, which prevents DNA replication in bacteria. The chemical structure of AZD1480 consists of a 4-morpholinyl group attached to a 4-[[5-chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl group. It is classified as a synthetic compound with an unknown pharmacokinetic profile.

Fórmula: C₁₇H₂₀ClN₅O₃

Pureza: Min. 95%

Peso molecular: 377.83 g/mol

Ref: 3D-BEC75881