CAS 1384071-99-1

Fórmula: C22H19F4N7O

InChI: InChI=1S/C22H19F4N7O/c1-11(2)33-20-17(19(27)28-10-29-20)18(32-33)12-3-6-14(7-4-12)30-21(34)31-16-9-13(22(24,25)26)5-8-15(16)23/h3-11H,1-2H3,(H2,27,28,29)(H2,30,31,34)

Clave InChI: CYORWDWRQMVGHN-UHFFFAOYSA-N

SMILES: CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)N

1-(4-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenyl)-3-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Urea

CAS: 1384071-99-1

1-(4-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenyl)-3-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Urea

Fórmula: C₂₂H₁₉F₄N₇O

Pureza: >99%

Peso molecular: 473.43

Ref: 54-PC108618

AD80

CAS: 1384071-99-1

AD80

Fórmula: C₂₂H₁₉F₄N₇O

Pureza: ≥98%

Peso molecular: 473.43

Ref: 54-BUP09552

AD80

CAS: 1384071-99-1

1-(4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

Fórmula: C₂₂H₁₉F₄N₇O

Pureza: 99+%

Peso molecular: 473.43

Ref: IN-DG00798649

AD80

CAS: 1384071-99-1

AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.

Fórmula: C₂₂H₁₉F₄N₇O

Pureza: 99.49% - 99.75%

Forma y color: Solid

Peso molecular: 473.4262

Ref: TM-T4301

AD80

CAS: 1384071-99-1

AD80 is a multi-kinase inhibitor that prevents the phosphorylation and activation of tyrosine kinases. It has been shown to inhibit the proliferation of leukemia cells in vivo. AD80 has been found to be effective against glioblastoma cells and other cancer types, such as melanoma, breast cancer, and lung cancer. AD80 inhibits protein synthesis by binding to the ATP-binding site of the enzyme kinase domain. The solubility data for AD80 shows that it is highly soluble in water and organic solvents.

Fórmula: C₂₂H₁₉F₄N₇O

Pureza: Min. 95%

Peso molecular: 473.43 g/mol

Ref: 3D-JFC07199