CAS 13870-90-1: Coenzima B12
Descripción:Coenzima B12, también conocido como metilcobalamina, es un cofactor vital en varios procesos bioquímicos, particularmente en el metabolismo de la homocisteína y la síntesis de metionina. Es una vitamina soluble en agua que pertenece al complejo de vitaminas B, específicamente al grupo B12, que incluye varias formas de cobalamina. Caracterizado por su estructura compleja, Coenzima B12 contiene un ion de cobalto en su núcleo, coordinado a un anillo de corrina, y se distingue por la presencia de un grupo metilo. Este compuesto juega un papel crucial en el metabolismo celular, particularmente en el sistema nervioso central y en la formación de glóbulos rojos. La deficiencia de Coenzima B12 puede llevar a problemas de salud significativos, incluyendo anemia y trastornos neurológicos. Se obtiene principalmente a través de fuentes dietéticas, particularmente productos de origen animal, y es esencial para mantener una función neurológica adecuada y la síntesis de ADN. Además, Coenzima B12 se utiliza a menudo en entornos clínicos para tratar deficiencias y condiciones de salud relacionadas.
Fórmula:C72H100CoN18O17P
InChI:InChI=1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;-1;+3/p-2/t31-,34-,35-,36-,37+,41-,52?,53-,56-,57+,59-,60+,61+,62+;4-,6-,7-,10-;/m11./s1
Clave InChI:InChIKey=OAJLVMGLJZXSGX-RQKYJTTQSA-L
SMILES:O=C(N)CCC1C=2C=C3[N]4=C(C(=C5[N-]6C7C(CC(=O)N)C5(C)CCC(=O)NCC(OP(=O)([O-])OC8C(O)C(OC8CO)N9C=[N](C=%10C=C(C(=CC%109)C)C)[Co+3]4%116([N]2C(=C(C%12=[N]%11C7(C)C(C)(CC(=O)N)C%12CCC(=O)N)C)C1(C)CC(=O)N)[CH2-]C%13OC(N%14C=NC=%15C(=NC=NC%15%14)N)C(O)C%13O)C)C)C(CCC(=O)N)C3(C)C
- Sinónimos:
- (5'-Deoxy-5'-adenosyl)cobamide coenzyme
- (5,6-Dimethylbenzimidazolyl)Cobamide Coenzyme
- 5'-Deoxy-5'-adenosylcobalamin
- 5'-Deoxyadenosyl vitamin B12
- 5'-Deoxyadenosyl-5,6-dimethylbenzimidazolylcobamide
- 5'-Deoxyadenosylcobalamin
- 5,6-Dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide
- 5,6-Dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide
- 5′-Deoxyadenosyl vitamin B<sub>12</sub>
- Actimide
- Ver más sinónimos
- Adenosyl B12
- Adenosyl B<sub>12</sub>
- Adenosylcobalamin
- Anabasi
- Betarin
- Calomide
- Cobalamin coenzyme
- Cobalamin, Co-(5'-deoxy-5'-adenosyl)-
- Cobalion
- Cobamamid
- Cobamamida
- Cobamamide
- Cobamide coenzyme, (5'-deoxy-5'-adenosyl)-
- Cobamide coenzyme, (5,6-dimethyl-1H-benzimidazolyl)-
- Cobamide, Co-(5'-deoxy-5'-adenosyl)-α-(5,6-dimethyl-1H-benzimidazolyl)-
- Cobanzyme
- Cobatlamin S
- Cobazymase
- Cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
- Cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
- Cobinamide, Co-(5'-deoxyadenosine-5') derivative hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
- Cobinamide, Co-(5′-deoxyadenosin-5′-yl)-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN<sup>3</sup>)
- Cobinamide, Co-(5′-deoxyadenosine-5′) deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
- Cobinamide, Co-(5′-deoxyadenosine-5′) deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
- Coenzile
- Coenzyme B12
- Coenzyme B<sub>12</sub>
- DBC
- DBC coenzyme
- Dbcc
- Deoxyadenosylcobalamin
- Dibencozide
- Dibenzcozamide
- Dimebenzcozamide
- Dolonevran
- Enzicoba
- Funacomide
- Heraclene
- Hi-Fresmin
- Hycobal
- Indusil
- Lm 176
- Represil
- Sabalamin
- Vitamin B12 coenzyme
- Vitamin B12, Co-(5'-deoxy-5'-adenosyl) deriv.
- Vitamin B<sub>12</sub> coenzyme
- Vitamin B<sub>12</sub>, Co-(5′-deoxy-5′-adenosyl) deriv.
- Xobaline
- α-(5,6-Dimethylbenzimidazolyl)-Co-5'-deoxyadenosylcobamide
- α-(5,6-Dimethylbenzimidazolyl)cobamide coenzyme
- coenzyme B12 crystalline
- Cobinamide, Co-(5′-deoxyadenosin-5′-yl)-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3)
- adenosyl cobalamine
