
CAS 1393465-84-3
:Fórmula:C24H22F2N6O3S
InChI:InChI=1S/C24H22F2N6O3S/c1-3-32(2)36(34,35)31-19-7-6-18(25)20(21(19)26)22(33)17-12-30-24-16(17)8-14(9-29-24)15-10-27-23(28-11-15)13-4-5-13/h6-13,31H,3-5H2,1-2H3,(H,29,30)
Clave InChI:DKNZQPXIIHLUHU-UHFFFAOYSA-N
SMILES:CCN(C)S(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CN=C(N=C4)C5CC5)F
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N'-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-N-ethyl-N-methylsulfamide
CAS:Fórmula:C24H22F2N6O3SPureza:%Peso molecular:512.5317PLX7904
CAS:PLX7904 is a small molecule that binds to the active site of DNA polymerase alpha and inhibits its activity. It has been shown to inhibit the production of suppressor genes in human cells, which may be responsible for the suppression of autoimmune diseases and cancer. PLX7904 also has an effect on probiotic bacteria by binding to iron, which is necessary for their survival. PLX7904 can bind to a variety of molecules through hydrogen bonds, including DNA and iron-containing proteins. This drug has been shown to have synergistic effects with other drugs when used in cell culture studies.
Fórmula:C24H22F2N6O3SPureza:Min. 95%Peso molecular:512.53 g/molPLX7904
CAS:PLX7904 (PB04), a selective RAF inhibitor, blocks ERK1/2 in mutant BRAF melanoma without activating it in RAS mutants.Fórmula:C24H22F2N6O3SPureza:99.51% - 99.66%Forma y color:SolidPeso molecular:512.532



