CAS 1404-93-9

Vancomicina, hidrocloruro

Descripción:

La vancomicina hidrocloruro es un antibiótico glucopéptido que se utiliza principalmente para tratar infecciones bacterianas graves, particularmente aquellas causadas por bacterias Gram-positivas, incluyendo Staphylococcus aureus resistente a meticilina (MRSA). Se caracteriza por su estructura compleja, que incluye una serie de aminoácidos y moieties de azúcar que contribuyen a su mecanismo de acción. La vancomicina actúa inhibiendo la síntesis de la pared celular en las bacterias, lo que lleva a la lisis celular y a la muerte. La forma hidrocloruro mejora su solubilidad en agua, haciéndola adecuada para la administración intravenosa. Se administra típicamente en un entorno clínico debido a su potencia y la necesidad de monitorear posibles efectos secundarios, como la nefrotoxicidad y la ototoxicidad. La vancomicina también es notable por su espectro de actividad, que está limitado a ciertos tipos de bacterias, y a menudo se reserva para casos en los que otros antibióticos son ineficaces. Su uso está guiado por pruebas de susceptibilidad para asegurar la efectividad y combatir el desarrollo de resistencia a los antibióticos.

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·xClH

InChI: InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1

Clave InChI: InChIKey=LCTORFDMHNKUSG-XTTLPDOESA-N

SMILES: O(C=1C2=CC3=CC1OC=4C(Cl)=CC(=CC4)[C@@H](O)[C@@H](NC([C@@H](CC(C)C)NC)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@]3(C(=O)N[C@@]5(C=6C=C(C=7C([C@@H](C(O)=O)NC(=O)[C@]([C@H](O)C=8C=C(Cl)C(O2)=CC8)(NC5=O)[H])=CC(O)=CC7O)C(O)=CC6)[H])[H])[C@H]9[C@H](O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)[C@@H](O)[C@H](O)[C@@H](CO)O9.Cl

Sinónimos:

• (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (non-preferred name)
• (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (non-preferred name)
• (3S-(3R*,6S*(S*),7S*,22S*,23R*,26R*,36S*,38aS*))-3-(2-Amino-2-oxoethyl)-44-((2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((4-methyl-2-(methylamino)-1-oxopentyl)amino)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid, monohydrochloride
• 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, vancomycin deriv.
• 48-({3-[(4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl}oxy)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (1:1) (non-preferred name)
• Laikexin
• Lyphocin
• Unii-71Wo621Tjd
• Vancocin hydrochloride
• Vancocine hydrochloride
• Vancocyn
• Vancomycin HCl
• Vancomycin monohydrochloride
• Vancor

Vancomycin hydrochloride, Molecular Biology Grade

CAS: 1404-93-9

Vancomycin hydrochloride, 1404-93-9, is a polypeptide with antibiotic properties suitable for laboratory study of bacterial infections. Learn more at Thermo Fisher Scientific.

Fórmula: C₆₆H₇₆Cl₃N₉O₂₄

Forma y color: White to tan to brown, Free-flowing powder

Peso molecular: 1485.72

Ref: 02-J62790

Vancomycin hydrochloride, 50 mg/ml in distilled water, sterile-filtered

CAS: 1404-93-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J67251

Vancomycin Hydrochloride

CAS: 1404-93-9

Forma y color: Neat

Ref: 61-FOR0239.00

SECOND INTERNATIONAL STANDARD FOR VANCOMYCIN

CAS: 1404-93-9

SECOND INTERNATIONAL STANDARD FOR VANCOMYCIN

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄

Peso molecular: 1449.254

Ref: 41-ISA_39036

VANCOMYCIN FOR SYSTEM SUITABILITY CRS

CAS: 1404-93-9

VANCOMYCIN FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002080

VANCOMYCIN HYDROCHLORIDE CRS

CAS: 1404-93-9

VANCOMYCIN HYDROCHLORIDE CRS

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄

Forma y color: White. Powder.

Peso molecular: 1449.254

Ref: 41-V0045000

Vancomycin B with Monodechlorovancomycin

CAS: 1404-93-9

Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoi

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Forma y color: Off-White Tan Powder

Peso molecular: 1483.40688

Ref: 45-1709018

Vancomycin B

CAS: 1404-93-9

Antibiotics nesoi

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Forma y color: White Brown Powder

Peso molecular: 1483.40688

Ref: 45-1709029

Vancomycin, hydrochloride

CAS: 1404-93-9

Fórmula: C₆₆H₇₆Cl₃N₉O₂₄

Pureza: 95%

Forma y color: Solid

Peso molecular: 1485.7145

Ref: IN-DA001CD1

Vancomycin hydrochloride

CAS: 1404-93-9

Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!

Fórmula: C₆₆H₇₆Cl₃N₉O₂₄

Pureza: 97.20% - 99.19%

Forma y color: Off White Powder

Peso molecular: 1485.71

Ref: TM-T0832

Vancomycin hydrochloride

CAS: 1404-93-9

Vancomycin hydrochloride

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Pureza: Heavy metals: <30 ppm. (Typical Value in Batch COA)

Forma y color: white. almost white or tan to brown free flowing powder

Peso molecular: 1,485.71g/mol

Ref: 54-BIV0155

Vancomycin hydrochloride, low endotoxin

CAS: 1404-93-9

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Pureza: ≤ 5.0%

Forma y color: White to tan powder

Peso molecular: 1485.73

Ref: 7W-GP4819

Vancomycin hydrochloride

CAS: 1404-93-9

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Pureza: ≤ 5.0%

Forma y color: White to tan powder

Peso molecular: 1485.73

Ref: 7W-GA6284

Vancomycin hydrochloride BioChemica

CAS: 1404-93-9

Vancomycin hydrochloride BioChemica

Forma y color: Solid

Peso molecular: 1,485.71g/mol

Ref: 54-BIA1839

Vancomycin hydrochloride

Producto controlado

CAS: 1404-93-9

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Forma y color: Neat

Peso molecular: 1485.71

Ref: 04-C17900500

Vancomycin Hydrochloride

Producto controlado

CAS: 1404-93-9

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Forma y color: Neat

Peso molecular: 1485.71

Ref: 86-MM0239.00

Vancomycin solution

CAS: 1404-93-9

Vancomycin solution

Forma y color: Solution

Peso molecular: 1,485.71g/mol

Ref: 54-BIG1035

Vancomycin Hydrochloride RS

CAS: 1404-93-9

Forma y color: White Solid Powder

Ref: 2K-7000800021

Vancomycin Hydrochloride (90%)

CAS: 1404-93-9

Stability Hygroscopic
Applications Vancomycin Hydrochloride is an antibiotic used against gram-positive bacterial strains.
References Yao, N., et al.: Biopolymers, 90, 421 (2008); Lai, H., et al.: ACS Appl. Mater. Interfaces, 7, 2046 (2015);

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Pureza: 90%

Forma y color: Neat

Peso molecular: 1485.71

Ref: TR-V096533

Vancomycin HCl - pharma grade

CAS: 1404-93-9

Vancomycin is a tricyclic glycopeptide antibiotic that has bactericidal effects against staphylococci, streptococci, and other gram-positive bacteria. It is often used as an alternative treatment for severe staphylococcal and streptococcal infections, including endocarditis, and infections with MRSA (methicillin-resistant Staphylococcus aureus), penicillin-resistant pneumococci or in cases of allergy to penicillins and cephalosporins.

Fórmula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Forma y color: Powder

Peso molecular: 1,485.71 g/mol

Ref: 3D-AV11352