CAS 1415637-72-7

Fórmula: C20H18F3N7

InChI: InChI=1S/C20H18F3N7/c1-28-17(12-4-6-13(7-5-12)20(21,22)23)14(10-26-28)16-15-18(29(2)27-16)24-11-25-19(15)30-8-3-9-30/h4-7,10-11H,3,8-9H2,1-2H3

Clave InChI: SHAVEYUXRBIMLA-UHFFFAOYSA-N

SMILES: CN1C(=C(C=N1)C2=NN(C3=C2C(=NC=N3)N4CCC4)C)C5=CC=C(C=C5)C(F)(F)F

4-(1-Azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS: 1415637-72-7

4-(1-Azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1H-pyrazolo[3,4-d]pyrimidine

Fórmula: C₂₀H₁₈F₃N₇

Pureza: ≥98% (HPLC)

Peso molecular: 413.4

Ref: 54-PC1030064

PF-05085727

CAS: 1415637-72-7

PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.

Fórmula: C₂₀H₁₈F₃N₇

Pureza: 98%

Forma y color: Solid

Peso molecular: 413.399

Ref: TM-T16482

4-(1-Azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS: 1415637-72-7

Fórmula: C₂₀H₁₈F₃N₇

Pureza: 98%

Forma y color: Solid

Peso molecular: 413.3990

Ref: IN-DA01E6OD

PF 05085727

CAS: 1415637-72-7

Inhibitor of cGMP-dependent phosphodiesterase 2A (PDE2A) with IC50 = 2 nM and has higher affinity over other phosphodiesterases (> 500-fold). Increases cGMP in rodent brain in vivo. Reverses anxiolytic behaviour, enhances performance of new object recognition and social recognition tasks.  Potentiates NMDA signalling and reverses behavioural effects of NMDA antagonists.

Fórmula: C₂₀H₁₈F₃N₇

Pureza: Min. 95%

Forma y color: White To Off-White Solid

Peso molecular: 413.4 g/mol

Ref: 3D-BP165159