CAS 1421936-85-7

Iclepertin

Fórmula: C₂₀H₁₈F₆N₂O₅S

InChI: InChI=1S/C20H18F6N2O5S/c1-10(19(21,22)23)32-14-4-3-12(34(2,30)31)5-13(14)17(29)28-8-11-7-18(11,9-28)15-6-16(33-27-15)20(24,25)26/h3-6,10-11H,7-9H2,1-2H3/t10-,11+,18+/m1/s1

Clave InChI: MYHDQTVHHMSLEF-DDBGAENHSA-N

SMILES: C[C@H](C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2C[C@@H]3C[C@@]3(C2)C4=NOC(=C4)C(F)(F)F

Sinónimos:

• [5-Methanesulfonyl-2-((R)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-[(1R,5R)-1-(5-trifluoromethyl-isoxazol-3-yl)-3-aza-bicyclo[3.1.0]
• Methanone, [5-(methylsulfonyl)-2-[(1R)-2,2,2-trifluoro-1-methylethoxy]phenyl][(1R,5R)-1-[5-(trifluoromethyl)-3-isoxazolyl]-3-azabicyclo[3.1.0]hex-3-yl]-
• [5-Methanesulfonyl-2-((R)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-[(1R,5R)-1-(5-trifluoromethyl-isoxazol-3-yl)-3-aza-bicyclo
• Iclepertin
• Iclepertin (BI-425809)

Iclepertin

CAS: 1421936-85-7

Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.

Fórmula: C₂₀H₁₈F₆N₂O₅S

Pureza: 99.21% - 99.66%

Forma y color: Solid

Peso molecular: 512.423

Ref: TM-T37089

Iclepertin

CAS: 1421936-85-7

Iclepertin

Fórmula: C₂₀H₁₈F₆N₂O₅S

Pureza: ≥98%

Peso molecular: 512.42

Ref: 54-BUP02852

(5-(Methylsulfonyl)-2-(((R)-1,1,1-trifluoropropan-2-yl)oxy)phenyl)((1R,5R)-1-(5-(trifluoromethyl)isoxazol-3-yl)-3-azabicyclo[3.1.0]hexan-3-yl)methanone

CAS: 1421936-85-7

Fórmula: C₂₀H₁₈F₆N₂O₅S

Pureza: 99%

Peso molecular: 512.4227

Ref: IN-DA01WSTW

Iclepertin

CAS: 1421936-85-7

(5-(Methylsulfonyl)-2-(((R)-1,1,1-trifluoropropan-2-yl)oxy)phenyl)((1R,5R)-1-(5-(trifluoromethyl)isoxazol-3-yl)-3-azabicyclo[3.1.0]hexan-3-yl)methanone

Fórmula: C₂₀H₁₈F₆N₂O₅S

Pureza: 99%

Peso molecular: 512.42

Ref: IN-DG01407226

[5-​(Methylsulfonyl)​-​2-​[(1R)​-​2,​2,​2-​trifluoro-​1-​methylethoxy]​phenyl]​[(1R,​5R)​-​1-​[5-​(trifluoromethyl)​-​3-​isoxazolyl]​-​3-​azabicyclo[3.1.0]​hex-​3-​yl]​-methanone

Producto controlado

CAS: 1421936-85-7

Fórmula: C₂₀H₁₈F₆N₂O₅S

Forma y color: Neat

Peso molecular: 512.423

Ref: TR-M416050

BI 425809

CAS: 1421936-85-7

BI 425809 is a drug that belongs to the class of selective serotonin reuptake inhibitors (SSRIs) and has been shown in clinical studies to be effective in the treatment of depression. The safety profile of BI 425809 has been established in clinical trials with healthy Chinese subjects, where it was found that the drug had no harmful effects at doses up to 400 mg/day. The concentration-time curve for BI 425809 showed an interactive response with food intake, which may indicate a need for dosage adjustment when taken with food. Pharmacokinetic properties have been evaluated in healthy Chinese subjects, showing that oral absorption is rapid and complete; elimination is mainly by hepatic metabolism; and elimination half-life is approximately 12 hours. BI 425809 has a low potential for abuse as it does not bind to dopamine receptors or produce any rewarding effects.

Pureza: Min. 95%

Ref: 3D-FM180750