CAS 1428728-83-9

Fórmula: C44H36N8O2S2

InChI: InChI=1S/C44H36N8O2S2/c1-45-41(53)29-11-3-5-15-35(29)55-43-27-19-17-25(23-33(27)49-51-43)37-39(31-13-7-9-21-47-31)38(40(37)32-14-8-10-22-48-32)26-18-20-28-34(24-26)50-52-44(28)56-36-16-6-4-12-30(36)42(54)46-2/h3-24,37-40H,1-2H3,(H,45,53)(H,46,54)(H,49,51)(H,50,52)

Clave InChI: AMFHQHPHCWAIPO-UHFFFAOYSA-N

SMILES: CNC(=O)C1=CC=CC=C1SC2=NNC3=C2C=CC(=C3)C4C(C(C4C5=CC=CC=N5)C6=CC7=C(C=C6)C(=NN7)SC8=CC=CC=C8C(=O)NC)C9=CC=CC=N9

Axitinib Dimer

CAS: 1428728-83-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₄₄H₃₆N₈O₂S₂

Peso molecular: 772.24026

Ref: 45-1A17310

2,2'-((3,3'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide)

CAS: 1428728-83-9

Fórmula: C₄₄H₃₆N₈O₂S₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 772.9390

Ref: IN-DA01X1E7

Axitinib Impurity 2

CAS: 1428728-83-9

Fórmula: C₄₄H₃₆N₈O₂S₂

Forma y color: White To Off-White Solid

Peso molecular: 772.95

Ref: 4Z-A-188003

2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide)

Producto controlado

CAS: 1428728-83-9

Applications 2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide) is an impurity of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),

Fórmula: C₄₄H₃₆N₈O₂S₂

Forma y color: Neat

Peso molecular: 722.94

Ref: TR-D493388

Axitinib dimer Impurity 2

CAS: 1428728-83-9

Fórmula: C₄₄H₃₆N₈O₂S₂

Peso molecular: 772.95

Ref: ST-EA-CP-A34024