CAS 1443763-60-7

Fórmula: C29H26FN5O4S

InChI: InChI=1S/C29H26FN5O4S/c1-18(19-4-9-22(30)10-5-19)28(36)31-23-11-6-20(7-12-23)21-8-15-27-33-29(34-35(27)17-21)32-25-14-13-24(40(3,37)38)16-26(25)39-2/h4-18H,1-3H3,(H,31,36)(H,32,34)/t18-/m1/s1

Clave InChI: NRJKIOCCERLIDG-GOSISDBHSA-N

SMILES: C[C@H](C1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)C3=CN4C(=NC(=N4)NC5=C(C=C(C=C5)S(=O)(=O)C)OC)C=C3

Empesertib

CAS: 1443763-60-7

Empesertib

Fórmula: C₂₉H₂₆FN₅O₄S

Pureza: 99%

Peso molecular: 559.61

Ref: 54-BUP12554

(R)-2-(4-Fluorophenyl)-N-(4-(2-((2-Methoxy-4-(Methylsulfonyl)Phenyl)Amino)-[1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)Phenyl)Propanamide

CAS: 1443763-60-7

(R)-2-(4-Fluorophenyl)-N-(4-(2-((2-Methoxy-4-(Methylsulfonyl)Phenyl)Amino)-[1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)Phenyl)Propanamide

Fórmula: C₂₉H₂₆FN₅O₄S

Pureza: 99%

Peso molecular: 559.61

Ref: 54-PC108719

(R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide

CAS: 1443763-60-7

Fórmula: C₂₉H₂₆FN₅O₄S

Pureza: 99%

Forma y color: Solid

Peso molecular: 559.6112

Ref: IN-DA00ABOG

Empesertib

CAS: 1443763-60-7

Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.

Fórmula: C₂₉H₂₆FN₅O₄S

Pureza: 97.45% - 99.4%

Forma y color: Solid

Peso molecular: 559.611

Ref: TM-T8487

(R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide

CAS: 1443763-60-7

(R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide

Fórmula: C₂₉H₂₆FN₅O₄S

Pureza: 99%

Peso molecular: 559.61

Ref: IN-DG630298

BAY1161909

CAS: 1443763-60-7

BAY1161909 is a water-soluble drug that inhibits tumor growth by inhibiting Plk1. It has shown effective dose to be 5mg/kg. The cellular mechanism of BAY1161909 is CDK4/6 inhibition, which can lead to cell cycle arrest and apoptosis. BAY1161909 has been shown to inhibit the growth of colon cancer cells in vitro and in vivo. BAY1161909 also showed potent antitumor activity in a mouse xenograft model of human melanoma, with efficacy equivalent to that observed with other anticancer drugs used for this indication.

Fórmula: C₂₉H₂₆FN₅O₄S

Pureza: Min. 95%

Peso molecular: 559.61 g/mol

Ref: 3D-BB177693