CAS 145100-51-2

N-(5-cloro-2-piridil)bis(trifluorometanosulfonimida)

Descripción:

N-(5-cloro-2-piridil)bis(trifluorometanosulfonamida), con el número CAS 145100-51-2, es un compuesto químico caracterizado por su estructura única, que incluye un anillo de piridina sustituido con un átomo de cloro y dos grupos trifluorometanosulfonamida. Este compuesto es típicamente un sólido a temperatura ambiente y es conocido por su alta estabilidad térmica y solubilidad en disolventes orgánicos polares. La presencia de grupos trifluorometanosulfonamida confiere una fuerte acidez y lo convierte en un potente electrófilo, que puede ser utilizado en diversas reacciones químicas, incluyendo sustituciones nucleofílicas y como reactivo en síntesis orgánica. Además, el sustituyente de cloro en el anillo de piridina puede influir en la reactividad del compuesto y su interacción con otras especies químicas. Debido a sus propiedades, este compuesto puede encontrar aplicaciones en farmacéuticos, agroquímicos y ciencia de materiales, particularmente en el desarrollo de líquidos iónicos y como catalizador en transformaciones orgánicas. Se deben observar precauciones de seguridad al manipular este compuesto, ya que puede representar riesgos para la salud.

Fórmula: C₇H₃ClF₆N₂O₄S₂

InChI: InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H

Clave InChI: InChIKey=TUFGVZMNGTYAQD-UHFFFAOYSA-N

SMILES: N(S(C(F)(F)F)(=O)=O)(S(C(F)(F)F)(=O)=O)C1=CC=C(Cl)C=N1

Sinónimos:

• 1-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(Trifluoromethanesulfonyl)Amino]-5-Chloropyridine
• 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine
• Bistrifluoromethylsulfonylaminochloropyridine
• Comins
• Comins' reagent
• Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-
• N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridinamine
• N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine
• N-(5-Chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
• N-(5-Chloro-2-pyridyl)-N-(trifluoromethanesulfonyl)trifluoromethanesulfonamide
• N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
• N-(5-Chloro-2-pyridyl)triflimide
• N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
• NSC 683533
• N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE)
• 2-[N,N-bis(trifluoromethylsulphony)amino]-5-chloropyridine
• n-(5-chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide
• 2-N,N-Bis(trifluoromethanesulfonyl)aminoü-5-chloropyridine, 99%
• N-(5-chloro-2-pyridyl)bis(trifluromethanesulfonimide
• 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]
• Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: >96.0%(GC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 392.67

Ref: 3B-B1865

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99%

CAS: 145100-51-2

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuk

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 99%

Forma y color: White to pale yellow or cream, Crystalline powder

Peso molecular: 392.67

Ref: 02-L16929

Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 392.6831

Ref: IN-DA001KJZ

2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine

CAS: 145100-51-2

2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: ≥95%

Forma y color: Off-white Solid

Peso molecular: 392.68313

Ref: 54-PC3128

N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: ≥ 98.0%

Forma y color: White to orange or brown powder or solid

Peso molecular: 392.68

Ref: 7W-GX3787

Comin's reagent

CAS: 145100-51-2

Comin's reagent is a sulfonation agent that reacts with an enolate and forms a sulfonic acid. The reaction can be used to synthesize chiral compounds. Comin's reagent is selective for the (R) configuration of acetylcholine and can be used to synthesize α-amino acids from chiral alcohols and esters. Comin's reagent is also used in the synthesis of neurotrophic or growth factor compounds, which are proteins that promote cell growth or differentiation. These functional groups are found in natural products such as nicotinic acetylcholine, thallusin, and growth factor.

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 392.68 g/mol

Ref: 3D-FC10786

2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine

CAS: 145100-51-2

2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 98%

Peso molecular: 392.68

Ref: IN-DG4062

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 95%

Forma y color: Solid, Chunks or Crystalline Powder

Peso molecular: 392.67

Ref: 10-F009051

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

Producto controlado

CAS: 145100-51-2

Stability Moisture Sensitive, Unstable in DMSO Solution
Applications 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine also known as Comins’ Reagent is used as a triflyl compouind in the synthesis of vinyl triflates from metallo enolates.
References Comins, D., et al.: Tetrahedron Lett., 33, 6299 (1992);

Fórmula: C₇H₃ClF₆N₂O₄S₂

Forma y color: Neat

Peso molecular: 392.68

Ref: TR-B585565