CAS 149263-94-5

6'-metil-2-piridinil-2-(acetilamino)-2-desoxi-1-tio-B-D-glucopiranósido

Descripción:

6'-metil-2-piridinil-2-(acetilamino)-2-desoxi-1-tio-B-D-glucopiranósido, con el número CAS 149263-94-5, es un compuesto químico que pertenece a la clase de los glucósidos, específicamente un tio-glucósido. Este compuesto presenta un anillo de piridina, que contribuye a sus propiedades aromáticas, y un grupo tiol que reemplaza el oxígeno típico en el enlace glucosídico, mejorando su reactividad y potencial actividad biológica. La presencia de un grupo acetilamino indica que puede participar en diversas interacciones bioquímicas, potencialmente influyendo en su solubilidad y estabilidad. El grupo metilo en el anillo de piridina puede afectar las propiedades electrónicas del compuesto y la hindrance estérica, lo que puede jugar un papel en su interacción con objetivos biológicos. En general, las características estructurales únicas de este compuesto sugieren aplicaciones potenciales en química medicinal, particularmente en el desarrollo de terapias o como sonda bioquímica, aunque las actividades biológicas específicas requerirían una investigación adicional.

Fórmula: C14H20N2O5S

InChI: InChI=1S/C14H20N2O5S/c1-7-4-3-5-10(15-7)22-14-11(16-8(2)18)13(20)12(19)9(6-17)21-14/h3-5,9,11-14,17,19-20H,6H2,1-2H3,(H,16,18)/t9-,11-,12-,13-,14+/m1/s1

Clave InChI: XUKXHOMZOIYNLR-FZGMBXNASA-N

SMILES: CC1=NC(=CC=C1)S[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C

Sinónimos:

• Mpt-Nag
• 6-methyl-2-pyridinyl-2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside
• 6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-beta-D-glucopyranoside

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

CAS: 149263-94-5

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

Fórmula: C₁₄H₂₀N₂O₅S

Pureza: ≥95%

Peso molecular: 328.38

Ref: 54-OR1129828

6-Methyl-2-pyridinyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

Ref: 7W-GC6100

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a thioglycoside derivative featuring an N-acetyl-D-glucosamine moiety connected via a beta-thioglycosidic linkage to a 6-methyl-2-pyridyl aglycone. The thioether bond confers resistance to enzymatic hydrolysis by glycosidases while maintaining recognition by sugar-binding proteins. This thioglycoside is used as a stable substrate analog in glycosidase inhibition studies and as a probe for lectin-carbohydrate interaction mapping.

Fórmula: C₁₄H₂₀N₂O₅S

Peso molecular: 328.384

Ref: TM-TXB-00173

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

CAS: 149263-94-5

Fórmula: C₁₄H₂₀N₂O₅S

Pureza: 95%

Peso molecular: 328.3840

Ref: IN-DA001LIH

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

The 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a chloride salt that has been used in the laboratory to develop an analytical method for the determination of glucose in urine samples. The bioavailability of 6MP is low and it is excreted by renal filtration, so this compound has been used as a marker for renal transplantation. Glomerular filtration rate (GFR) is reduced in diabetic patients, leading to a decrease in the amount of 6MP excreted. This drug can be administered orally or intravenously and has shown efficacy at low dose levels. Low doses have also been associated with decreased detection sensitivity due to its low level of excretion, which makes it an ideal candidate for use as a biomarker for chronic kidney disease. A chronic kidney disease animal model was used to study the effects on GFR and creatinine clearance rates

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 328.39 g/mol

Ref: 3D-EM10847