CAS 14937-32-7
:Penta-O-galoyl-β-D-glucosa
Descripción:
Penta-O-galoyl-β-D-glucosa es un compuesto polifenólico derivado de la glucosa, caracterizado por la presencia de cinco grupos galoyl esterificados a los grupos hidroxilo de la molécula de glucosa. Este compuesto exhibe fuertes propiedades antioxidantes, que se atribuyen a la presencia de múltiples grupos hidroxilo fenólicos que pueden eliminar radicales libres. Penta-O-galoyl-β-D-glucosa es conocido por sus posibles beneficios para la salud, incluyendo actividades antiinflamatorias, antimicrobianas y anticancerígenas, lo que lo convierte en un tema de interés en la investigación farmacológica y nutracéutica. Su solubilidad es generalmente mayor en disolventes orgánicos en comparación con el agua, lo que puede influir en su biodisponibilidad y aplicación en diversas formulaciones. La estabilidad del compuesto puede verse afectada por factores como el pH y la temperatura, que son consideraciones importantes en su almacenamiento y uso. Además, su complejidad estructural contribuye a sus interacciones únicas con los sistemas biológicos, mejorando aún más su potencial como agente terapéutico. En general, Penta-O-galoyl-β-D-glucosa representa un área significativa de estudio en el campo de los productos naturales y la química medicinal.
Fórmula:C41H32O26
InChI:InChI=1S/C41H32O26/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16/h1-10,27,33-35,41-56H,11H2/t27-,33-,34+,35-,41+/m1/s1
Clave InChI:InChIKey=QJYNZEYHSMRWBK-NIKIMHBISA-N
SMILES:O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC(=O)C4=CC(O)=C(O)C(O)=C4)O[C@H](COC(=O)C5=CC(O)=C(O)C(O)=C5)[C@H]2OC(=O)C6=CC(O)=C(O)C(O)=C6
Sinónimos:- 1,2,3,4,6-O-Pentagalloylglucose
- 1,2,3,4,6-Penta-O-Galloyl-B-D-Glucopyranose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucoside
- 1,2,3,4,6-Penta-O-galloyl-β-glucopyranose
- 1,2,3,4,6-Penta-O-galloylglucose
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucose
- 1,2,3,4,6-Pentagalloylglucose
- 1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose
- Db 03208
- G 7548
- Gallic acid, pentaester with β-<span class="text-smallcaps">D</span>-glucopyranose
- Gallotannin 15
- Glucopyranose, pentagallate, β-<span class="text-smallcaps">D</span>-
- PGG
- Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose
- Penta-O-galloylglucose
- Penta-Ortho-Galloylglucose
- Pentagalloyl Glucose
- Pentagalloyl-<span class="text-smallcaps">D</span>-glucose
- Pentagalloylglucose
- beta-penta-O-galloyl-glucose
- β-1,2,3,4,6-Pentagalloylglucose
- β-<span class="text-smallcaps">D</span>-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
- β-<span class="text-smallcaps">D</span>-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
- Glucopyranose, pentagallate, β-D-
- β-D-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
- 1,2,3,4,6-Pentagalloyl-β-D-glucose
- β-D-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
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(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetrakis(3,4,5-Trihydroxybenzoate)
CAS:(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetrakis(3,4,5-Trihydroxybenzoate)Fórmula:C41H32O26Pureza:98%Peso molecular:940.68Pentagalloylglucose
CAS:PentagalloylglucoseFórmula:C41H32O26Pureza:≥98%Forma y color:SolidPeso molecular:940.681,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose
CAS:Fórmula:C41H32O26Pureza:(HPLC) ≥ 98.0%Forma y color:White to yellow or light brown powderPeso molecular:940.68β-D-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
CAS:Fórmula:C41H32O26Pureza:98%Forma y color:SolidPeso molecular:940.6772Pentagalloylglucose (Standard)
CAS:Pentagalloylglucose (Standard) is a reference standard for research and analysis in studies involving Pentagalloylglucose. 1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses potent anti-proliferative and anti-invasive effects, it also has inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity. 3. PGG may serve as a model for the development of new types of anti-diabetic and anti-metabolic syndrome therapeutics. 4. 1, 2, 3, 4, 6-Penta- O -galloyl-β- d -glucose has vasodilatory and anti-inflammatory effects, it dilates vascular smooth muscle and suppresses the vascular inflammatory process via endothelium-dependent nitric oxide (NO)/cGMP signaling. 5. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose can decrease the level of extracellular hepatitis B virus (HBV) (IC5, 1. microg/ml) in a dose-dependent manner, it also can reduce the HBsAg level by 25% at a concentration of 4 microg/ml; the gallate structure of PGG may play a critical role in the inhibition of anti-HBV activity, suggests that PGG could be a candidate for developing an anti-HBV agent. 6. 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose has anti-parasitic activity, displays an EC5 value of 67 μM, at least 6.6-fold more effective than the standard drug benznidazole against trypomastigote forms of T. cruzi.Fórmula:C41H32O26Peso molecular:940.67721,2,3,4,6-Penta-O-galloyl-b-D-glucopyranose (>85%)
CAS:Producto controladoStability Hygroscopic, Temperature Sensitive
Applications Found to exhibit in vitro growth-inhibiting effect on human hepatocellular carcinoma cell line, SK-HEP-1 cells.
References Oh, G-S, et al.: Cancer Letters, 174, 17 ( 2001)Fórmula:C41H32O26Pureza:>85%Forma y color:NeatPeso molecular:940.681,2,3,4,6-O-pentagalloylglucose
CAS:(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4,5-trihydroxybenzoate)Fórmula:C41H32O26Pureza:98%Peso molecular:940.68Pentagalloylglucose
CAS:1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities.Fórmula:C41H32O26Pureza:99.17% - 99.97%Forma y color:Gray SolidPeso molecular:940.67721,2,3,4,6-Pentagalloyl β-D-glucose
CAS:Natural glycosideFórmula:C41H32O26Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:940.691,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose
CAS:A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.Fórmula:C41H32O26Pureza:Min. 96 Area-%Forma y color:PowderPeso molecular:940.68 g/molPentagalloylglucose - Bio-X ™
CAS:A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.Fórmula:C41H32O26Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:940.68 g/mol
