CAS 1510-21-0

Hemisucinato de colesterol

Descripción:

Hemisucinato de colesterol es un derivado del colesterol, caracterizado por la presencia de un grupo hemisuccinato unido a la estructura del colesterol. Este compuesto se utiliza típicamente en aplicaciones bioquímicas y farmacéuticas, particularmente en sistemas de liberación de fármacos y como componente en formulaciones liposomales. Exhibe propiedades anfifílicas, lo que significa que tiene características tanto hidrofílicas (que atraen agua) como hidrofóbicas (que repelen el agua), lo que lo hace útil para formar bicapas lipídicas y micelas. Hemisucinato de colesterol puede mejorar la solubilidad de fármacos hidrofóbicos y facilitar su transporte a través de membranas biológicas. Además, se conoce por su capacidad para formar complejos estables con varias biomoléculas, lo que puede ser beneficioso en la liberación dirigida de fármacos. El compuesto se considera generalmente biocompatible, lo que lo hace adecuado para su uso en aplicaciones farmacéuticas. Sus características estructurales contribuyen a su papel en la modificación de las propiedades de la membrana e influyendo en las interacciones celulares, que son críticas en el desarrollo de nuevas estrategias terapéuticas.

Fórmula: C₃₁H₅₀O₄

InChI: InChI=1S/C31H50O4/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1

Clave InChI: InChIKey=WLNARFZDISHUGS-MIXBDBMTSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C[C@@H](OC(CCC(O)=O)=O)CC2)[H])[H]

Sinónimos:

• 3-(3-Cholesteryloxycarbonyl)propionic acid
• 3-Cholesteryloxycarbonylpropanoic acid
• 3-[(Cholest-5-en-3β-yl)oxycarbonyl]propionic acid
• 4-(Cholest-5-En-3-Yloxy)-4-Oxobutanoic Acid
• 4-[(3Beta)-Cholest-5-En-3-Yloxy]-4-Oxobutanoic Acid
• Chems
• Cholest-5-en-3-ol (3β)-, 3-(hydrogen butanedioate)
• Cholest-5-en-3-ol (3β)-, hydrogen butanedioate
• Cholesterol hemisuccinate
• Cholesterol hydrogen succinate
• Cholesterol monosuccinate
• Cholesteryl Hemisuccinate
• Cholesteryl hydrogen succinate
• Cholesteryl hydrogen succinate Cholesteryl hemisuccinate
• Cholesteryl monosuccinate
• Mono(cholesteryl) succinate
• Succinate cholesterol monoester

Cholesterol Hydrogen Succinate

CAS: 1510-21-0

Fórmula: C₃₁H₅₀O₄

Pureza: >97.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 486.74

Ref: 3B-C0674

Cholesteryl hemisuccinate

CAS: 1510-21-0

Pureza: 98%

Peso molecular: 486.37

Ref: 10-F556402

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl Hemisuccinate

Fórmula: C₃₁H₅₀O₄

Pureza: ≥95%

Peso molecular: 486.73

Ref: 54-BUP18726

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl Hemisuccinate

Fórmula: C₃₁H₅₀O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 486.73

Ref: 54-OR1030148

Cholesteryl hemisuccinate

CAS: 1510-21-0

Fórmula: C₃₁H₅₀O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 486.7263

Ref: IN-DA001N0N

Cholesteryl Hemisuccinate

Producto controlado

CAS: 1510-21-0

Applications Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.
References Domingues, N., et al.; Biochim. Biophys. Acta, Mol. Cell Biol. Lipids, 1862, 210 (2017)

Fórmula: C₃₁H₅₀O₄

Forma y color: Neat

Peso molecular: 486.73

Ref: TR-C432586

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl hemisuccinate

Fórmula: C₃₁H₅₀O₄

Pureza: 95%

Peso molecular: 486.73

Ref: IN-DG84780

Cholesteryl Hemisuccinate

CAS: 1510-21-0

Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective,

Fórmula: C₃₁H₅₀O₄

Pureza: 97.07% - 99.98%

Forma y color: Solid

Peso molecular: 486.7263

Ref: TM-T67509

Cholesterol hydrogen succinate

Producto controlado

CAS: 1510-21-0

Cholesterol hydrogen succinate is a cholesterol derivative that inhibits the activity of various receptors, including the LDL-receptor which is involved in the uptake of cholesterol from the blood. It also has inhibitory properties against infectious diseases and can be used as an experimental model for coronary heart disease. Cholesterol hydrogen succinate has been shown to inhibit the phase transition temperature (Tc) of human serum. This drug also possesses anti-oxidative properties and has been shown to have protective effects on mitochondrial membrane potential. The biological properties of this compound include its ability to induce hemisuccinate formation by hydrolyzing cholesteryl esters and inhibit endoxifen activity.

Fórmula: C₃₁H₅₀O₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 486.73 g/mol

Ref: 3D-FC61971