CAS 1617-53-4

Amentoflavona

Descripción:

Amentoflavona es un compuesto biflavonoide que se encuentra principalmente en varias plantas, particularmente en el género Selaginella y algunas especies del árbol Ginkgo biloba. Se caracteriza por su estructura única, que consiste en dos unidades de flavona unidas por un átomo de carbono central. Este compuesto exhibe una variedad de actividades biológicas, incluyendo propiedades antioxidantes, antiinflamatorias y potenciales anticancerígenas. Amentoflavona ha sido estudiado por sus efectos en varias vías celulares, incluidas las involucradas en la apoptosis y la proliferación celular. Además, ha mostrado promesas en la mejora de la función cognitiva y en la exhibición de efectos neuroprotectores. El compuesto es soluble en disolventes orgánicos, pero tiene una solubilidad limitada en agua, lo que puede afectar su biodisponibilidad. Debido a sus diversas propiedades farmacológicas, Amentoflavona es de interés tanto en la química medicinal como en la investigación de productos naturales, con estudios en curso que exploran sus posibles aplicaciones terapéuticas. Al igual que con muchos compuestos naturales, se necesita más investigación para comprender completamente sus mecanismos de acción y posibles usos en entornos clínicos.

Fórmula: C₃₀H₁₈O₁₀

InChI: InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H

Clave InChI: InChIKey=YUSWMAULDXZHPY-UHFFFAOYSA-N

SMILES: OC=1C(=C2C(C(=O)C=C(O2)C3=CC=C(O)C=C3)=C(O)C1)C4=CC(=CC=C4O)C=5OC=6C(C(=O)C5)=C(O)C=C(O)C6

Sinónimos:

• 3′′′,8-Biflavone, 4′,4′′′,5,5′′,7,7′′-hexahydroxy-
• 4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-
• 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
• Amenthoflavone
• Ginkgetin, didemethyl-
• I3′,II8-Biapigenin
• Nsc 295677
• Tridemethylsciadopitysin
• Amentoflavone

Amentoflavone

CAS: 1617-53-4

Amentoflavone

Fórmula: C₃₀H₁₈O₁₀

Pureza: >99%

Peso molecular: 538.46

Ref: 54-OR1025435

Amentoflavone

CAS: 1617-53-4

Fórmula: C₃₀H₁₈O₁₀

Pureza: ≥ 98.0%

Forma y color: White to yellow powder

Peso molecular: 538.46

Ref: 7W-GT1823

Amentoflavone

CAS: 1617-53-4

Amentoflavone

Fórmula: C₃₀H₁₈O₁₀

Pureza: 99.5%

Peso molecular: 538.46

Ref: 54-BUP12114

Amentoflavone (Standard)

CAS: 1617-53-4

Amentoflavone (Standard) is a reference standard for research and analysis in studies involving Amentoflavone. Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhibitor of human cathepsin B. It has antimalarial activity in trials significant affinities towards the Delta-1, kappa opioid receptors (as an antagonist) and binds to benzodiazepine receptors. Amentoflavone may be a potential lead for a new type of anti-inflammatory agents having the dual inhibitory activity of group II phospholipase A2 and cyclooxygenase. Amentoflavone and quercetin differentially exerted suppression of PGE2 biosynthesis via downregulation of COX-2/iNOS expression.

Fórmula: C₃₀H₁₈O₁₀

Peso molecular: 538.4579

Ref: TM-TMSM-2838

Amentoflavone

CAS: 1617-53-4

Amentoflavone, a biflavonoid with antiinflammatory activity, inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells.

Fórmula: C₃₀H₁₈O₁₀

Pureza: 95%~99%

Forma y color: Yellow powder

Peso molecular: 538.464

Ref: BP-BP0161

Amentoflavone

CAS: 1617-53-4

Amentoflavone analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₃₀H₁₈O₁₀

Pureza: (HPLC) ≥99%

Forma y color: Powder

Peso molecular: 538.46

Ref: 11-1057S

Amentoflavone

CAS: 1617-53-4

Fórmula: C₃₀H₁₈O₁₀

Forma y color: Neat

Peso molecular: 538.46

Ref: TR-A576420

Amentoflavone

CAS: 1617-53-4

Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.

Fórmula: C₃₀H₁₈O₁₀

Pureza: 98.81% - 99.78%

Forma y color: Yellow Solid

Peso molecular: 538.4579

Ref: TM-T3417

Amentoflavone

CAS: 1617-53-4

8-(5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Fórmula: C₃₀H₁₈O₁₀

Pureza: 99%

Peso molecular: 538.46

Ref: IN-DG113814

Amentoflavone

CAS: 1617-53-4

Oxygen-heterocyclic compound

Fórmula: C₃₀H₁₈O₁₀

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 538.47

Ref: 5G-80351

Amentoflavone

CAS: 1617-53-4

Amentoflavone is a biflavonoid compound, which is a naturally occurring substance found in various plants such as Ginkgo biloba and Hypericum perforatum. Its molecular structure consists of two flavonoid units joined together, contributing to its unique biochemical characteristics. The source of amentoflavone spans across several medicinal plants, where it plays roles in the plants’ defense mechanisms.

Fórmula: C₃₀H₁₈O₁₀

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 538.46 g/mol

Ref: 3D-FA65485

Amentoflavone

CAS: 1617-53-4

Fórmula: C₃₀H₁₈O₁₀

Forma y color: Solid

Peso molecular: 538.5

Ref: BE-RMT17810

Amentoflavone

CAS: 1617-53-4

Fórmula: C₃₀H₁₈O₁₀

Pureza: 99%

Forma y color: Solid

Peso molecular: 538.4579

Ref: IN-DA001VTC