CAS 1628256-23-4

Fórmula: C26H34N8O

InChI: InChI=1S/C26H34N8O/c1-18(2)32-10-12-33(13-11-32)20-6-7-22(27-16-20)30-25-28-15-19-14-21-24(35)29-17-26(8-4-3-5-9-26)34(21)23(19)31-25/h6-7,14-16,18H,3-5,8-13,17H2,1-2H3,(H,29,35)(H,27,28,30,31)

Clave InChI: YPJRHEKCFKOVRT-UHFFFAOYSA-N

SMILES: CC(C)N1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6

Lerociclib

CAS: 1628256-23-4

Lerociclib

Fórmula: C₂₆H₃₄N₈O

Pureza: ≥98%

Peso molecular: 474.6

Ref: 54-BUP01744

Lerociclib

CAS: 1628256-23-4

2'-((5-(4-Isopropylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one

Fórmula: C₂₆H₃₄N₈O

Pureza: 99%

Peso molecular: 474.6

Ref: IN-DG766449

Lerociclib (G1T38)

CAS: 1628256-23-4

Lerociclib (G1T38) is a potent inhibitor of breast cancer cells with structural similarity to palbociclib. It is an inhibitor of the CDK4/6 complex that is responsible for cell cycle progression at G1 phase, as well as the retinoblastoma (RB) protein. The drug has been shown to inhibit tumor growth and induce apoptosis in xenograft tumor models. Lerociclib also inhibits the growth of cervical cancer cells in vitro and reduces tumor weight in a mouse model by inhibiting proliferation and inducing apoptosis.

Fórmula: C₂₆H₃₄N₈O

Pureza: Min. 95%

Peso molecular: 474.61 g/mol

Ref: 3D-DQC25623

Lerociclib

CAS: 1628256-23-4

Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.

Fórmula: C₂₆H₃₄N₈O

Pureza: 99.56%

Forma y color: Solid

Peso molecular: 474.6

Ref: TM-T11345