CAS 1629229-37-3

[(8R)-5,6-Dihidro-8-metil-3-(3-metil-1,2,4-tiadiazol-5-il)-1,2,4-triazolo[4,3-a]pirazin-7(8H)-il](4-fluorofenil)metanona

Descripción:

La sustancia química con el nombre "[(8R)-5,6-Dihidro-8-metil-3-(3-metil-1,2,4-tiadiazol-5-il)-1,2,4-triazolo[4,3-a]pirazin-7(8H)-il](4-fluorofenil)metanona" y número CAS "1629229-37-3" es un compuesto orgánico complejo caracterizado por su estructura de múltiples anillos, que incluye un moiety de triazol y pirazina. Este compuesto presenta un sustituyente de tiadiazol, lo que contribuye a su potencial actividad biológica. La presencia de un grupo fluorofenilo sugiere que puede exhibir propiedades electrónicas únicas, lo que podría influir en su reactividad e interacción con objetivos biológicos. La estereoquímica indicada por la configuración (8R) implica arreglos espaciales específicos que pueden afectar el perfil farmacológico del compuesto. Tales compuestos a menudo se investigan por sus posibles aplicaciones en química medicinal, particularmente en el desarrollo de fármacos dirigidos a diversas enfermedades. La estructura intrincada y los grupos funcionales sugieren que puede poseer propiedades interesantes, incluidas posibles actividades antimicrobianas o anticancerígenas, aunque se necesitarían datos biológicos específicos para confirmar estos efectos.

Fórmula: C₁₆H₁₅FN₆OS

InChI: InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1

Clave InChI: InChIKey=PPSNFPASKFYPMN-SECBINFHSA-N

SMILES: C[C@@H]1C=2N(C(=NN2)C=3SN=C(C)N3)CCN1C(=O)C4=CC=C(F)C=C4

Sinónimos:

• (R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
• [(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone
• (4-Fluorophenyl)[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]methanone
• Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
• Fezolinetant
• ESN 364
• Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
• FEZOLINETANT; ESN-364; ESN 364; ESN364

Fezolinetant

CAS: 1629229-37-3

Fórmula: C₁₆H₁₅FN₆OS

Pureza: 98%

Forma y color: Solid

Peso molecular: 358.3933

Ref: IN-DA01EOC7

Fezolinetant

CAS: 1629229-37-3

Fezolinetant

Fórmula: C₁₆H₁₅FN₆OS

Pureza: ≥98%, 10 mM in DMSO

Peso molecular: 358.39

Ref: 54-BUP04385

Fezolinetant

CAS: 1629229-37-3

Fezolinetant (ESN-364) is a neurokinin-3 receptor antagonist that is being investigated for menopausal hot flashes.Cost-effective and quality-assured.

Fórmula: C₁₆H₁₅FN₆OS

Pureza: 98.62% - 99.7%

Forma y color: Solid

Peso molecular: 358.39

Ref: TM-T15278

Fezolinetant-d4

CAS: 1629229-37-3

Fórmula: C₁₆H₁₁D₄FN₆OS

Peso molecular: 362.42

Ref: 4Z-F-240002

Fezolinetant

CAS: 1629229-37-3

Fórmula: C₁₆H₁₅FN₆OS

Peso molecular: 358.40

Ref: 4Z-F-240001

Fezolinetant

CAS: 1629229-37-3

(R)-(4-Fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone

Fórmula: C₁₆H₁₅FN₆OS

Pureza: 98%

Peso molecular: 358.39

Ref: IN-DG00858361

FEZOLINETANT

CAS: 1629229-37-3

Pureza: 98%

Peso molecular: 358.3999939

Ref: 10-F842003

Fezolinetant

CAS: 1629229-37-3

Fezolinetant is a drug for the treatment of menopausal symptoms. It is designed to be administered as a single dose, with the primary analysis being a questionnaire on the frequency and severity of symptoms. Fezolinetant has been shown to be efficacious in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Fezolinetant also prevents cancer in mice by inhibiting the invasion and migration of tumor cells. The drug binds to receptors in cells that are involved in cancer cell growth and proliferation, which blocks the production of proteins that are essential for tumor cell division. This drug also has an efficient method of delivery, which may reduce side effects.

Fórmula: C₁₆H₁₅FN₆OS

Pureza: Min. 95%

Peso molecular: 358.39 g/mol

Ref: 3D-EQC22937