CAS 1660117-38-3

3(2H)-Piridazinona, 2,4-dimetil-6-[1-[(1S)-1-feniletil]-6-(tetrahidro-2H-piran-4-il)-1H-imidazo[4,5-c]piridin-2-il]-

Descripción:

3(2H)-Piridazinona, 2,4-dimetil-6-[1-[(1S)-1-feniletil]-6-(tetrahidro-2H-piran-4-il)-1H-imidazo[4,5-c]piridin-2-il]- es un compuesto orgánico complejo caracterizado por su estructura multicíclica, que incluye un núcleo de piridazinona y varios sustituyentes que contribuyen a sus propiedades químicas. La presencia del grupo imidazo[4,5-c]piridina sugiere una posible actividad biológica, ya que los compuestos con tales estructuras a menudo se investigan para aplicaciones farmacológicas. Los grupos dimetilo indican que el compuesto puede exhibir propiedades estéricas y electrónicas específicas, influyendo en su reactividad e interacciones con objetivos biológicos. Además, la presencia de un grupo feniletil y un grupo tetrahidro-2H-piran puede aumentar la lipofilia, afectando potencialmente la solubilidad y permeabilidad del compuesto. En general, las características estructurales únicas de este compuesto sugieren que puede tener un comportamiento químico interesante y aplicaciones potenciales en química medicinal, aunque las actividades biológicas específicas requerirían una investigación adicional a través de estudios experimentales.

Fórmula: C₂₅H₂₇N₅O₂

InChI: InChI=1S/C25H27N5O2/c1-16-13-21(28-29(3)25(16)31)24-27-22-15-26-20(19-9-11-32-12-10-19)14-23(22)30(24)17(2)18-7-5-4-6-8-18/h4-8,13-15,17,19H,9-12H2,1-3H3/t17-/m0/s1

Clave InChI: InChIKey=QNFGQQDKBYVNAS-KRWDZBQOSA-N

SMILES: [C@@H](C)(N1C(=NC=2C1=CC(=NC2)C3CCOCC3)C=4C=C(C)C(=O)N(C)N4)C5=CC=CC=C5

Sinónimos:

• BI 894999
• 3(2H)-Pyridazinone, 2,4-dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-
• 2,4-Dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-3(2H)-pyridazinone

BRD4 Inhibitor-10

CAS: 1660117-38-3

BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).

Fórmula: C₂₅H₂₇N₅O₂

Pureza: 99.53%

Forma y color: White Solid

Peso molecular: 429.5142

Ref: TM-T14776

BRD4 Inhibitor-10

CAS: 1660117-38-3

BRD4 Inhibitor-10

Fórmula: C₂₅H₂₇N₅O₂

Pureza: 99.5%

Peso molecular: 429.51

Ref: 54-BUP08530

(S)-2,4-Dimethyl-6-(1-(1-Phenylethyl)-6-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazo[4,5-c]Pyridin-2-Yl)Pyridazin-3(2H)-One

CAS: 1660117-38-3

(S)-2,4-Dimethyl-6-(1-(1-Phenylethyl)-6-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazo[4,5-c]Pyridin-2-Yl)Pyridazin-3(2H)-One

Fórmula: C₂₅H₂₇N₅O₂

Pureza: 97%

Peso molecular: 429.51

Ref: 54-OR1023847

(S)-2,4-Dimethyl-6-(1-(1-Phenylethyl)-6-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazo[4,5-c]Pyridin-2-Yl)Pyridazin-3(2H)-One

CAS: 1660117-38-3

Fórmula: C₂₅H₂₇N₅O₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 429.5142

Ref: IN-DA01PR6J

BRD4 Inhibitor-10

CAS: 1660117-38-3

(S)-2,4-Dimethyl-6-(1-(1-phenylethyl)-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl)pyridazin-3(2H)-one

Fórmula: C₂₅H₂₇N₅O₂

Pureza: 97%

Peso molecular: 429.51

Ref: IN-DG00944730

BET BRD4 inhibitor compound II-25

CAS: 1660117-38-3

BET BRD4 inhibitor compound II-25 belongs to a class of protein inhibitors. It is orally available and can inhibit cancer cells in vitro. BET BRD4 inhibitor compound II-25 has been shown to induce cell maturation and apoptosis in myeloid leukemia cells. This drug also inhibits the methyltransferase activity of the enzyme, thereby preventing the production of inflammatory cytokines that cause inflammation. In addition, this drug has shown potential as an anticancer therapeutic by inhibiting cancer cell proliferation and inducing tumor necrosis in vivo. It is possible that BET BRD4 inhibitor compound II-25 may function as a toll-like receptor modulator because it can block TLR signaling pathways in mice.

Fórmula: C₂₅H₂₇N₅O₂

Pureza: Min. 95%

Peso molecular: 429.51 g/mol

Ref: 3D-KRC11738