CAS 16679-58-6

Desmopresina

Descripción:

Desmopresina es un análogo sintético de la vasopresina, una hormona que ocurre de forma natural y que regula la retención de agua en el cuerpo. Se utiliza principalmente en el tratamiento de condiciones como la diabetes insípida y la enuresis nocturna. Desmopresina exhibe una alta afinidad por los receptores V2 de vasopresina, que se localizan principalmente en los riñones, lo que lleva a un aumento en la reabsorción de agua y a una reducción en la producción de orina. La sustancia se caracteriza por su capacidad para aumentar la concentración de orina sin afectar significativamente la presión arterial, lo que la convierte en una opción preferida para pacientes con necesidades médicas específicas. Desmopresina se administra típicamente en varias formas, incluyendo aerosol nasal, tabletas orales y soluciones inyectables. Su farmacocinética indica una vida media relativamente larga en comparación con la vasopresina natural, lo que permite una dosificación menos frecuente. Además, Desmopresina generalmente es bien tolerado, aunque los efectos secundarios potenciales pueden incluir dolor de cabeza, náuseas y, en casos raros, retención de agua que puede llevar a hiponatremia. En general, Desmopresina es un agente terapéutico valioso en el manejo de ciertos trastornos relacionados con el equilibrio hídrico en el cuerpo.

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

InChI: InChI=1/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1

Clave InChI: NFLWUMRGJYTJIN-PNIOQBSNSA-N

SMILES: C1C[C@H](N(C1)C(=O)[C@@H]2CSSCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N

Sinónimos:

• 1-(3-Mercaptopropanoic acid)-8-D-argininevasopressin
• 1-{[(4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-arginylglycinamide
• 16679-58-6
• 240-726-7
• glycinamide, 1-[[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-arginyl-
• Octostim
• 1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N~5~-(diaminomethylidene)-D-ornithylglycinamide
• (1-Deamino-8-D-Arg)-vasopressin
• [1-β-Mercaptopropionic acid-8-D-arginine]vasopressin
• [Deamino1-D-arginine8]vasopressin
• [Desamino-Cys1,D-Arg8]vasopressin
• 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin
• 1: PN: US20020013262 PAGE: 2 claimed protein
• 1-Deamino-[8-D-arginine]vasopressin
• 1-Deamino-1-[D-Arg8]-vasopressin
• 1-Desamino-8-D-arginine-vasopressin
• 1-Desaminocystine-8-D-arginine-vasopressin
• 45: PN: WO2005000360 SEQID: 40 claimed protein
• 8-D-Arginine deaminovasopressin
• Adiuretin
• Adiuretin SD
• DAV Ritter
• Ddavp
• Desmopresina
• Desmopressine
• Desmospray
• Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-D-arginyl-, cyclic (1→5)-disulfide
• Minirin
• Minrin
• Peptide, (Xaa-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly), ?
• Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-
• Vasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-
• (Deamino-Cys1,D-Arg8)-Vasopressin acetate salt
• 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 acetate salt (Disulfide bond)
• [DEAMINO1, DARG8] VASOPRESSIN
• [deamino-cys1, d-arg8]-vasopressin acetate hydrate
• [deamino-Cys
• DESMOPRESSIN, HUMAN
• MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• [Deamino1,DArg8] Vasopressin (dDAVP) Desmopressin
• 3-MERCAPTOPROPIONYL-YFQNCPRG (DISULFIDE BRIDGE: 1-6)
• DESMOPRESSIN
• M.W. 1069.22 C46H64N14O12S2
• MAP-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• 3-Mercapto(1)propionyl-L-Tyr-L-Phe-L-Gln-L-Asn-L-Cys(1)-L-Pro-D-Arg-Gly-NH2
• 3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• DDAVP, HUMAN
• DESMOPRESSIN ACETATE PH. EUR.
• DESAMINO-[D-ARG8]VASOPRESSIN
• [DEAMINO-CYS1, D-ARG8]-VASOPRESSIN

(Deamino-Cys¹,D-Arg⁸)-Vasopressin

CAS: 16679-58-6

Desmopressin (DDAVP), as the first vasopressin analog with a very high and very specific antidiuretic effect, has been widely used for different therapeutic purposes. DDAVP also improves human learning and memory processes. CAS Number (desmopressin acetate): 62288-83-9.

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Pureza: 99.7%

Forma y color: White Powder

Peso molecular: 1069.23

Ref: 01-4012273

Desmopressin impurity standard

CAS: 16679-58-6

Desmopressin impurity standard

Forma y color: Off-White

Ref: 47-1188

Desmopressin

CAS: 16679-58-6

Desmopressin

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Forma y color: Off White Solid

Peso molecular: 1068.42696

Ref: 47-381

Desmopressin

CAS: 16679-58-6

Desmopressin (DDAVP)(DDAVP) is the synthetic analogue of the antidiuretic hormone arginine vasopressin.Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Pureza: 97.45%

Peso molecular: 1069.217

Ref: TM-T5019

Desmopressin

CAS: 16679-58-6

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Forma y color: White To Off-White Solid

Peso molecular: 1069.22

Ref: 4Z-PD-821

Desmopressin Trifluoroacetate

CAS: 16679-58-6

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂·C₂HF₃O₂

Forma y color: Off-White Solid

Peso molecular: 1069.24 114.02

Ref: 4Z-PD-8212

Desmopressin Acetate

CAS: 16679-58-6

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Pureza: 95%~99%

Forma y color: White to Off-white Powder

Peso molecular: 1069.22

Ref: BP-BPPG021

(D-Asn)-Desmopressin

Producto controlado

CAS: 16679-58-6

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂·x(C₂H₄O₂)

Forma y color: Neat

Peso molecular: 1069.2

Ref: TR-A788858

Asp(5)-Desmopressin Acetate Salt

Producto controlado

CAS: 16679-58-6

Fórmula: C₄₈H₆₈N₁₄O₁₄S₂

Forma y color: Neat

Peso molecular: 1129.27

Ref: TR-A788625

Desmopressin-[d5]

CAS: 16679-58-6

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Peso molecular: 1069.2

Ref: BE-MD-7637

Desmopressin

CAS: 16679-58-6

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Peso molecular: 1069.22

Ref: ST-EA-CP-D239000

Desmopressin

Producto controlado

CAS: 16679-58-6

Desmopressin is a synthetic analog of the natural hormone arginine vasopressin. It has been shown to be effective in the treatment of primary nocturnal enuresis, and a number of studies have reported that desmopressin is an effective therapy for idiopathic nocturnal enuresis. Desmopressin also has effects on water permeability, hemolysis, and protein synthesis. It increases the concentration of camp levels in urine and plasma while also inhibiting erythrocyte aggregation. Desmopressin has been shown to be more effective than placebo in women with primary nocturnal enuresis.

Fórmula: C₄₆H₆₄N₁₄O₁₂S₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 1,069.22 g/mol

Ref: 3D-FD110210