CAS 1715-30-6

Dihidrocloruro de alexidina

Descripción:

Dihidrocloruro de alexidina es un compuesto sintético utilizado principalmente como antiséptico y desinfectante. Pertenece a la clase de los biguanidas, que son conocidas por sus propiedades antimicrobianas. Esta sustancia se caracteriza por su capacidad para interrumpir las membranas celulares microbianas, lo que la hace efectiva contra un amplio espectro de bacterias, hongos y algunos virus. Dihidrocloruro de alexidina se presenta típicamente como un polvo blanco a blanco sucio y es soluble en agua, lo que facilita su aplicación en diversas formulaciones, incluidos enjuagues bucales y antisépticos tópicos. Su mecanismo de acción implica unirse a los componentes cargados negativamente de las membranas microbianas, lo que lleva a la lisis celular. Además, a menudo se prefiere en formulaciones debido a su relativamente baja toxicidad y potencial de irritación en comparación con otros antisépticos. Sin embargo, como todos los agentes químicos, debe usarse de acuerdo con las pautas de seguridad para minimizar los posibles efectos adversos. En general, Dihidrocloruro de alexidina es valorado tanto en productos clínicos como de consumo por su eficacia en el control de infecciones.

Fórmula: C₂₆H₅₈Cl₂N₁₀

InChI: InChI=1/C26H56N10.2ClH/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2;;/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36);2*1H

Clave InChI: InChIKey=BRJJFBHTDVWTCJ-UHFFFAOYSA-N

SMILES: C(CNC(NC(NCCCCCCNC(NC(NCC(CCCC)CC)=N)=N)=N)=N)(CCCC)CC.Cl

Sinónimos:

• 1,6-Bis(2-ethylhexylbiguanido)hexane dihydrochloride
• 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride
• 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2)
• 2,4,11,13-Tetraazatetradecanediimidamide, N¹,N¹⁴-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2)
• Alexidine dihydrochloride
• Alexidine hydrochloride
• Biguanide, 1,1′-hexamethylenebis[5-(2-ethylhexyl)-, dihydrochloride
• Hexamethylenebis(2-ethylhexyl)biguanide dihydrochloride
• N'',N''''''-hexane-1,6-diylbis[N'''-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride
• N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride
• WIN-21904
• Alexidine dihydrochloride, N,N''''-Hexane-1,6-diylbis[N'-(2-ethylhex-1-yl)(imidodicarbonimidic diamide)] dihydrochloride
• N,N''-Bis(2-ethylhexyl)-3,12-diiMino-2,4,11,13-tetraazatetradecanediiMidaMide
• Bisguanidine
• Bisguadine
• 1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride
• N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamidedihydrochloride
• Compound-904
• Sterwin 904

Alexidine Dihydrochloride

CAS: 1715-30-6

Fórmula: C₂₆H₅₆N₁₀·2HCl

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Almost white powder to crystaline

Peso molecular: 581.72

Ref: 3B-A3389

1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride

CAS: 1715-30-6

1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride

Fórmula: C₂₆H₅₆N₁₀·2ClH

Pureza: ≥95%

Forma y color: Solid-Powder

Peso molecular: 581.71172

Ref: 54-OR2503

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride

Fórmula: C₂₆H₅₈Cl₂N₁₀

Pureza: 99.5%

Peso molecular: 581.71

Ref: 54-BUP11753

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride: antifungal, antibiofilm, targets PTPMT1 for mitochondrial apoptosis, potential cancer treatment.

Fórmula: C₂₆H₅₈Cl₂N₁₀

Pureza: 99.32% - 99.81%

Forma y color: Solid

Peso molecular: 581.71

Ref: TM-T14177

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride

Fórmula: C₂₆H₅₆N₁₀·2ClH

Pureza: By hplc: 99.5% (Typical Value in Batch COA)

Forma y color: Solid

Peso molecular: 581.71172

Ref: 54-BIMI8260

Alexidine dihydrochloride

CAS: 1715-30-6

Fórmula: C₂₆H₅₆N₁₀·2HCl

Forma y color: White to off-white powder

Peso molecular: 581.71

Ref: 7W-GP3723

N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-Tetraazatetradecanediimidamide dihydrochloride

CAS: 1715-30-6

Fórmula: C₂₆H₅₈Cl₂N₁₀

Pureza: 98%

Forma y color: Solid

Peso molecular: 581.7117

Ref: IN-DA00ACX5

Alexidine Dihydrochloride

Producto controlado

CAS: 1715-30-6

Applications Alexidine Dihydrochloride has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii.
References Coburn, R.A., et al.: J. Med. Chem., 21, 8, 829 (1978), Takayama, K., et al.: J. Biol. Chem., 269, 2241 (1994), Faure, P., et al.: Biochimie, 86, 411 (2004),

Fórmula: C₂₆H₅₆N₁₀·2ClH

Forma y color: Neat

Peso molecular: 581.71

Ref: TR-A525000

Alexidine 2HCl

CAS: 1715-30-6

N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-Tetraazatetradecanediimidamide dihydrochloride

Fórmula: C₂₆H₅₈Cl₂N₁₀

Pureza: 98%

Peso molecular: 581.71

Ref: IN-DG284102

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride is a metabolic agent that belongs to the group of antimicrobial agents. It is used in the treatment of cervical cancer, which is caused by human papilloma virus. Alexidine dihydrochloride inhibits the growth of cancer cells and has been shown to induce cell death in squamous cancer cells. It also inhibits microbial infection when combined with polymyxin B. This compound binds to microbial membranes, disrupting their function and inhibiting bacterial growth. Alexidine dihydrochloride has been shown to inhibit the synthesis of DNA, RNA, and protein by binding to specific sites on cellular ribosomes.

Fórmula: C₂₆H₅₆N₁₀·2HCl

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 581.71 g/mol

Ref: 3D-BAA71530

Alexidine Dihydrochloride extrapure, 96%

CAS: 1715-30-6

Fórmula: C₂₅H₅₈C₁₂N₁₀

Pureza: min.96%

Forma y color: White to off-white, Powder

Peso molecular: 581.73

Ref: SR-67482