CAS 173676-60-3

(αS)-5-Cloro-α-(2-ciclopropiletinil)-2-[[(4-metoxifenil)metil]amino]-α-(trifluorometil)bencenometanol

Fórmula: C₂₁H₁₉ClF₃NO₂

InChI: InChI=1S/C21H19ClF3NO2/c1-28-17-7-4-15(5-8-17)13-26-19-9-6-16(22)12-18(19)20(27,21(23,24)25)11-10-14-2-3-14/h4-9,12,14,26-27H,2-3,13H2,1H3/t20-/m0/s1

Clave InChI: InChIKey=BXJWOBQJYQHISM-FQEVSTJZSA-N

SMILES: [C@](C#CC1CC1)([C@@](F)(F)F)(O)C2=C(NCC3=CC=C(OC)C=C3)C=CC(Cl)=C2

Sinónimos:

• (2S)-2-[5-Chloro-2-[(4-methoxyphenyl)methylamino]phenyl]-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
• (S)-5-chloro-a-(Cyclopropylacetenyl)-2-[((4-methoxyphenyl)methyl)amino]-a-(trifluoromethyl) benzenemethanol (E-4)
• (αS)-5-Chloro-α-(2-cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol
• Benzenemethanol, 5-chloro-a-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-a-(trifluoromethyl)-, (aS)-
• Benzenemethanol,5-chloro-a-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-a-(trifluoromethyl)-, (S)-
• Sd 572
• Benzenemethanol, 5-chloro-α-(2-cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)-, (αS)-

Efavirenz Impurity 14

CAS: 173676-60-3

Fórmula: C₂₁H₁₉ClF₃NO₂

Forma y color: White To Off-White Solid

Peso molecular: 409.83

Ref: 4Z-E-0736

(S)-5-Chloro-α-(2-cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoro-methyl)benzenemethanol

CAS: 173676-60-3

Forma y color: Neat

Ref: 86-MM0919.02

(S)-5-Chloro-Alpha-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-Alpha-(trifluoromethyl)benzenemethanol

Producto controlado

CAS: 173676-60-3

Applications (S)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol is the S enantiomer of rac-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol (C365145). (S)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol is also an impurity of Efavirenz (E425000), an HIV-1 reverse transcriptase inhibitor.
References Pierce, M., et al.: J. Org. Chem., 63, 8536 (1998)

Fórmula: C₂₁H₁₉ClF₃NO₂

Forma y color: Neat

Peso molecular: 409.83

Ref: TR-C366130

(S)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol-D4

Producto controlado

CAS: 173676-60-3

Fórmula: C₂₁D₄H₁₅ClF₃NO₂

Forma y color: Neat

Peso molecular: 413.854

Ref: TR-C366132