
CAS 17402-86-7
:Benzo[b]thiophene, 4-nitro-, 1,1-dioxide
Fórmula:C8H5NO4S
Sinónimos:- PHGDH-IN-5
- PHGDH-IN-5 (Compound B12)
- Benzo[b]thiophene, 4-nitro-, 1,1-dioxide
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PHGDH-IN-5
CAS:Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].Fórmula:C8H5NO4SForma y color:SolidPeso molecular:211.20
