CAS 1818885-28-7

Fórmula: C46H47ClN8O9S

InChI: InChI=1S/C46H47ClN8O9S/c1-26-27(2)65-46-39(26)41(29-7-9-30(47)10-8-29)50-35(42-53-52-28(3)54(42)46)25-38(57)49-31-11-13-32(14-12-31)64-24-23-63-22-21-62-20-19-61-18-17-48-34-6-4-5-33-40(34)45(60)55(44(33)59)36-15-16-37(56)51-43(36)58/h4-14,35-36,48H,15-25H2,1-3H3,(H,49,57)(H,51,56,58)/t35-,36?/m0/s1

Clave InChI: RWLOGRLTDKDANT-TYIYNAFKSA-N

SMILES: CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)OCCOCCOCCOCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8=CC=C(C=C8)Cl)C

ARV-825

CAS: 1818885-28-7

ARV-825

Fórmula: C₄₆H₄₇ClN₈O₉S

Pureza: ≥95%

Peso molecular: 923.43

Ref: 54-BUP04715

ARV-825

CAS: 1818885-28-7

ARV-825

Fórmula: C₄₆H₄₇ClN₈O₉S

Pureza: 98%

Forma y color: Solid

Peso molecular: 923.43158

Ref: 54-BIPC1022

ARV-825

CAS: 1818885-28-7

2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)ethoxy)phenyl)acetamide

Fórmula: C₄₆H₄₇ClN₈O₉S

Pureza: 98%

Peso molecular: 923.43

Ref: IN-DG630478

ARV-825

CAS: 1818885-28-7

ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.

Fórmula: C₄₆H₄₇ClN₈O₉S

Pureza: 97.15% - 98%

Forma y color: Solid

Peso molecular: 923.43

Ref: TM-T5434

ARV-825

CAS: 1818885-28-7

Pureza: 98%

Forma y color: Solid

Peso molecular: 923.44

Ref: 10-F986640

ARV-825

Producto controlado

CAS: 1818885-28-7

ARV-825 is a small molecule that inhibits the activity of enzymes in the secretase pathway, which are involved in the production of amyloid beta peptides. It has been shown to inhibit tumor growth in mouse xenografts with a significant cytotoxic effect. ARV-825 causes cell cycle arrest and apoptosis by inhibiting transcription-polymerase chain reaction and DNA synthesis. The molecule also inhibits Jak2 V617F, which is thought to be implicated in Alzheimer's disease. ARV-825 has been shown to significantly inhibit cell proliferation without any cytotoxicity at concentrations up to 100 μM.

Fórmula: C₄₆H₄₇ClN₈O₉S

Pureza: Min. 95%

Peso molecular: 923.43 g/mol

Ref: 3D-TXC88528