CAS 1871-22-3

Azul de tetrazolio

Descripción:

Azul de tetrazolio, también conocido como cloruro de 2,3,5-trifeniltetrazolio (TTC), es un compuesto químico comúnmente utilizado en aplicaciones biológicas y bioquímicas, particularmente en ensayos de viabilidad celular. Es un indicador redox que experimenta un cambio de color al ser reducido, convirtiéndose de una forma soluble amarilla a un producto de formazán rojo insoluble en presencia de células viables. Esta propiedad lo hace útil para evaluar la actividad metabólica en organismos vivos, ya que solo las células metabólicamente activas pueden reducir la sal de tetrazolio. Azul de tetrazolio se utiliza típicamente en microbiología, histología y diversas aplicaciones de investigación para evaluar la proliferación celular y la citotoxicidad. El compuesto es generalmente estable bajo condiciones de laboratorio estándar, pero debe manejarse con cuidado, ya que puede ser tóxico en ciertas concentraciones. Su solubilidad en agua y solventes orgánicos permite aplicaciones versátiles en diferentes configuraciones experimentales. En general, Azul de tetrazolio sirve como una herramienta valiosa en el estudio de procesos celulares y la evaluación de la salud celular.

Fórmula: C₄₀H₃₂N₈O₂·2Cl

InChI: InChI=1S/C40H32N8O2.2ClH/c1-49-37-27-31(23-25-35(37)47-43-39(29-15-7-3-8-16-29)41-45(47)33-19-11-5-12-20-33)32-24-26-36(38(28-32)50-2)48-44-40(30-17-9-4-10-18-30)42-46(48)34-21-13-6-14-22-34;;/h3-28H,1-2H3;2*1H/q+2;;/p-2

Clave InChI: InChIKey=MUUHXGOJWVMBDY-UHFFFAOYSA-L

SMILES: O(C)C1=C(N2[N+](=NC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)C=CC(=C1)C5=CC(OC)=C(C=C5)N6[N+](=NC(=N6)C7=CC=CC=C7)C8=CC=CC=C8.[Cl-]

Sinónimos:

• 2,2′,5,5′-Tetraphenyl-3,3′-(3,3′-dimethoxy-4,4′-diphenylene)ditetrazolium chloride
• 2,2′-(m,m′-Dimethoxy-p,p′-biphenylene)bis(3,5-diphenyltetrazolium chloride)
• 2H-Tetrazolium, 2,2′-(3,3′-dimethoxy[1,1′-biphenyl]-4,4′-diyl)bis[3,5-diphenyl-, chloride (1:2)
• 2H-Tetrazolium, 2,2′-(3,3′-dimethoxy[1,1′-biphenyl]-4,4′-diyl)bis[3,5-diphenyl-, dichloride
• 2H-Tetrazolium, 3,3′-(3,3′-dimethoxy-4,4′-biphenylylene)bis[2,5-diphenyl-, dichloride
• 3,3-(3,3-Dimethoxy-4,4-biphenylene)bis(2,5-diphenyl-2H-tetrazolium chloride)
• 3,3′-(3,3′-Dimethoxy-4,4′-biphenylylene)bis[2,5-diphenyl-2H-tetrazolium chloride]
• 3,3′-Dianisolebis[4,4′-(3,5-diphenyl)tetrazolium chloride]
• BT (dye)
• BTC
• Blue Tetrazolium chloride
• Ditetrazolium chloride
• NSC 27623
• Tetrazole blue
• Tetrazolium Blue BT
• Tetrazolium Blue Chloride
• Tetrazolium blue

Blue Tetrazolium [for Biochemical Research]

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: >95.0%(T)

Forma y color: White to Amber powder to crystal

Peso molecular: 727.65

Ref: 3B-B3581

Blue Tetrazolium

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: >95.0%(T)

Forma y color: White to Amber powder to crystal

Peso molecular: 727.65

Ref: 3B-D0943

Blue Tetrazolium chloride

CAS: 1871-22-3

Blue Tetrazolium chloride is useful in the prepartion of DNA cation complexes and immunoadsorbents for anti-DNA antibodies. It is used in assay of reducing sugars. In combination with 4-nitrocatechol, tetrazolium blue chloride forms a ternary complex with molybdenum(VI) for extraction and spectropho

Fórmula: C₄₀H₃₆Cl₂N₈O₂

Forma y color: Pale yellow to yellow, Powder

Peso molecular: 731.68

Ref: 02-A12502

3,3'-Dianisole-4,4'-bis(3,5-diphenyltetrazolium chloride

CAS: 1871-22-3

3,3'-Dianisole-4,4'-bis(3,5-diphenyltetrazolium chloride

Fórmula: C₄₀H₃₂N₈O₂·2Cl

Pureza: ≥98%

Forma y color: Pale yellow Solid-Powder

Peso molecular: 727.64048

Ref: 54-BIT3025

Blue Tetrazolium

CAS: 1871-22-3

Blue Tetrazolium (Tetrazolium blue), a dye used in microbial research, can be reduced to blue tetrazolium formazan (BTF). It determines succinate dehydrogenase (SDH) activity in yeast strains as a reduced substrate. Extract BTF using DMSO and test its absorption spectrum. BTF exhibits a wavelength range of 480-600 nm with maximal absorbance at 540 nm ^[1].

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Peso molecular: 727.64

Ref: TM-T85863

Tetrazolium Blue Chloride

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: (HPLC) ≥ 95.0%

Forma y color: Yellow powder

Peso molecular: 727.66

Ref: 7W-GT7170

3,3'-(3,3'-DIMETHOXY-[1,1'-BIPHENYL]-4,4'-DIYL)BIS(2,5-DIPHENYL-2H-TETRAZOL-3-IUM) CHLORIDE

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 727.6405

Ref: IN-DA007S1S

Tetrazolium Blue Chloride (>90%)

Producto controlado

CAS: 1871-22-3

Stability Light Sensitive
Applications Tetrazolium Blue Chloride is used for its anti-plasmodium activity. Also used in the study of inhibition of diphenyltetrazolium bromide (MTT) reduction by β-amyloid peptides resulting in neurodegenerative manifestations. Dyes and metabolites.
References Cui, X. et al.: Bioorg, Med. Chem., 16, 1927 (2008); Shearman, M. et al.: J. Neurochem, 65, 218 (1995);

Fórmula: C₄₀H₃₂N₈O₂·2Cl

Pureza: >90%

Forma y color: Neat

Peso molecular: 727.6

Ref: TR-T310700

Tetrazolium blue chloride

CAS: 1871-22-3

Tetrazolium blue chloride is a chemical compound that is used in the diagnosis of leukemia. It is a tetrazolium salt that reacts with reduced nicotinamide adenine dinucleotide (NADH) and produces an insoluble blue product. Tetrazolium blue chloride has been shown to be effective in treating human leukemic cells by causing DNA damage, which leads to cell death. Tetrazolium blue chloride has also been found to be an anti-inflammatory agent due to its ability to inhibit prostaglandin synthesis and production of reactive oxygen species.

Fórmula: C₄₀H₃₂N₈O₂·2Cl

Pureza: 90 To 110%

Forma y color: Yellow Powder

Peso molecular: 727.64 g/mol

Ref: 3D-ET11162

Blue Tetrazolium Chloride (BTC, Tetrazolium Blue Chloride) extrapure AR

CAS: 1871-22-3

Fórmula: C₄₀H₃₂O₂N₈Cl₂

Forma y color: Lemon yellow, Crystalline powder, Clear, Yellow

Peso molecular: 727.66

Ref: SR-22649