CAS 1962925-28-5

Fórmula: C23H29Cl2FN4O4

InChI: InChI=1S/C23H27FN4O4.2ClH/c1-23(2,30)15-10-25-11-17(15)27-21-13-8-19(31-3)20(32-4)9-16(13)26-22(28-21)14-7-12(24)5-6-18(14)29;;/h5-9,15,17,25,29-30H,10-11H2,1-4H3,(H,26,27,28);2*1H/t15-,17-;;/m1../s1

Clave InChI: VCFVLTMSBOZYOU-FXKISCCRSA-N

SMILES: CC(C)([C@@H]1CNC[C@H]1NC2=NC(=NC3=CC(=C(C=C32)OC)OC)C4=C(C=CC(=C4)F)O)O.Cl.Cl

CCT241533 dihydrochloride

CAS: 1962925-28-5

Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.

Fórmula: C₂₃H₂₉Cl₂FN₄O₄

Forma y color: Solid

Peso molecular: 515.41

Ref: TM-T36704