CAS 2029049-79-2

Fórmula: C21H21F3N2O3

InChI: InChI=1S/C21H21F3N2O3/c22-21(23,24)29-16-10-8-15(9-11-16)20(28)25-13-12-19(27)26-18-7-3-5-14-4-1-2-6-17(14)18/h1-2,4,6,8-11,18H,3,5,7,12-13H2,(H,25,28)(H,26,27)/t18-/m1/s1

Clave InChI: SGNRHEDBLPGDDC-GOSISDBHSA-N

SMILES: C1C[C@H](C2=CC=CC=C2C1)NC(=O)CCNC(=O)C3=CC=C(C=C3)OC(F)(F)F

ML390

CAS: 2029049-79-2

ML390 exerts its potent differentiation effect on multiple leukemia models.

Fórmula: C₂₁H₂₁F₃N₂O₃

Pureza: 99.76%

Forma y color: Solid

Peso molecular: 406.4

Ref: TM-T13774

(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide

CAS: 2029049-79-2

Fórmula: C₂₁H₂₁F₃N₂O₃

Pureza: 99%

Forma y color: Solid

Peso molecular: 406.3982

Ref: IN-DA01EPRB

ML390

CAS: 2029049-79-2

ML390

Fórmula: C₂₁H₂₁F₃N₂O₃

Pureza: ≥98%

Peso molecular: 406.4

Ref: 54-BUP06140

ML390

CAS: 2029049-79-2

(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide

Fórmula: C₂₁H₂₁F₃N₂O₃

Pureza: 99%

Peso molecular: 406.4

Ref: IN-DG764713

N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethoxy)-benzamide

CAS: 2029049-79-2

Pureza: 99%

Peso molecular: 406.4049988

Ref: 10-F866884

ML390

CAS: 2029049-79-2

ML390 is a potent and selective inhibitor of the enzyme 3-phosphoglycerate dehydrogenase (3PGDH). This enzyme catalyzes the conversion of 3-phosphoglycerate to glyceraldehyde-3-phosphate, which is an important step in the synthesis of pyrimidine nucleotides. ML390 inhibits this enzyme with high selectivity and potency. It has been shown to be effective against glioblastoma cells, which may be due to its ability to inhibit their growth by targeting enzymes involved in pyrimidine biosynthesis.

Fórmula: C₂₁H₂₁F₃N₂O₃

Pureza: Min. 95%

Peso molecular: 406.4 g/mol

Ref: 3D-EGD04979