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CAS 20554-84-1

:

(-)-Parthenolida

Descripción:
(-)-Parthenolida es un lactona sesquiterpénica derivada principalmente de la planta Tanacetum parthenium, comúnmente conocida como matricaria. Este compuesto se caracteriza por su estructura bicíclica única, que incluye un grupo funcional lactona. (-)-Parthenolida exhibe una variedad de actividades biológicas, incluyendo propiedades antiinflamatorias, anticancerígenas y antimicrobianas, lo que lo convierte en un tema de interés en la investigación farmacológica. Se sabe que inhibe la vía de señalización del factor nuclear kappa B (NF-κB), que juega un papel crucial en la inflamación y la progresión del cáncer. El compuesto se encuentra típicamente en forma líquida incolora a amarillo pálido y tiene un olor característico. Su solubilidad varía, siendo más soluble en disolventes orgánicos que en agua. Debido a sus posibles efectos terapéuticos, (-)-Parthenolida está siendo estudiado por su papel en el tratamiento de diversas condiciones, incluyendo migrañas y ciertos tipos de cáncer. Sin embargo, se necesita más investigación para comprender completamente sus mecanismos de acción y aplicaciones potenciales en medicina.
Fórmula:C15H20O3
InChI:InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11?,12-,13-,15+/m0/s1
Clave InChI:InChIKey=KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES:C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC\C(\C)=C\CC1)[H])[H])(O2)[H]
Sinónimos:
  • (1aR,4E,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (1aR,4Z,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (1aR,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (4E,7aS,10aS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (4Z)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • 2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
  • Germacra-1(10),11(13)-dien-12-oic acid, 4,5α-epoxy-6β-hydroxy-, γ-lactone
  • Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
  • Ver más sinónimos
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Encontrado 13 productos.
  • Parthenolide

    CAS:
    Parthenolide analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.
    Fórmula:C15H20O3
    Pureza:(HPLC) ≥95%
    Forma y color:Powder
    Peso molecular:248.33

    Ref: 11-3805

    20mg
    109,00€
  • PARTHENOLIDE CRS

    CAS:
    PARTHENOLIDE CRS

    Ref: 41-Y0001838

    15mg
    228,00€
  • Parthenolide

    CAS:
    Lactones, nesoi
    Fórmula:C15H20O3
    Forma y color:White Crystalline Powder
    Peso molecular:248.14124
  • Ref: IN-DA002A6V

    1g
    168,00€
    100mg
    91,00€
    250mg
    108,00€
  • Parthenolide

    CAS:
    Fórmula:C15H20O3
    Pureza:≥ 98.0%
    Forma y color:White, off-white or pale yellow-brown powder
    Peso molecular:248.32

    Ref: 7W-GP2300

    100mg
    89,00€
    250mg
    151,00€
    500mg
    234,00€
  • Parthenolide

    CAS:
    Parthenolide
    Fórmula:C15H20O3
    Pureza:By hplc: 99.88% (Typical Value in Batch COA)
    Forma y color: white crystals
    Peso molecular:248.32g/mol

    Ref: 54-BIP0110

    1g
    345,00€
    5g
    1.151,00€
    250mg
    123,00€
    500mg
    206,00€
  • Parthenolide

    CAS:
    Parthenolide
    Pureza:≥98%
    Peso molecular:248.32g/mol

    Ref: 54-BUP15119

    1g
    332,00€
    2g
    482,00€
    5g
    775,00€
    50mg
    80,00€
    100mg
    104,00€
    200mg
    180,00€
  • Parthenolide

    CAS:
    Fórmula:C15H20O3
    Pureza:95%~99%
    Peso molecular:248.322

    Ref: BP-BP1066

    20mg
    71,00€
    100mg
    118,00€
    1000mg
    209,00€
  • Parthenolide

    CAS:
    Fórmula:C15H20O3
    Pureza:>97.0%(HPLC)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:248.32

    Ref: 3B-P1982

    25mg
    58,00€
    100mg
    158,00€
  • Parthenolide

    CAS:
    Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.
    Fórmula:C15H20O3
    Pureza:98.19% - 99.46%
    Forma y color:White To Pale Yellow Crystalline Powder
    Peso molecular:248.32
  • Parthenolide

    CAS:
    Lactone
    Fórmula:C15H20O3
    Pureza:≥ 90.0 % (HPLC)
    Forma y color:Powder
    Peso molecular:248.32

    Ref: 5G-89255

    20mg
    166,00€
    50mg
    374,00€
    250mg
    1.598,00€
    500mg
    3.008,00€
    1000mg
    5.640,00€
  • Parthenolide

    CAS:
    <p>Parthenolide is a sesquiterpene lactone, which is a bioactive compound derived from the plant species Tanacetum parthenium, commonly known as feverfew. This compound is primarily isolated from the aerial parts of the plant, where it is found in highest concentrations within the flowers and leaves. Parthenolide exerts its effects through several biochemical pathways, including the inhibition of nuclear factor-kappa B (NF-κB) signaling, which plays a critical role in inflammatory and immune responses. Additionally, it disrupts the activity of certain kinases and modulates the expression of genes involved in cell cycle regulation and apoptosis.</p>
    Fórmula:C15H20O3
    Pureza:Min. 98 Area-%
    Forma y color:White Off-White Powder
    Peso molecular:248.32 g/mol

    Ref: 3D-FP65646

    1g
    355,00€
    2g
    497,00€
    5g
    778,00€
    10g
    1.128,00€
    500mg
    227,00€
  • Parthenolide

    CAS:
    <p>M02322 - Parthenolide</p>
    Fórmula:C15H20O3
    Pureza:97%
    Forma y color:Solid
    Peso molecular:248.322

    Ref: 10-M02322

    1g
    170,00€
    100mg
    80,00€
    250mg
    107,00€