CAS 20554-84-1
:(-)-Parthenolida
Descripción:
(-)-Parthenolida es un lactona sesquiterpénica derivada principalmente de la planta Tanacetum parthenium, comúnmente conocida como matricaria. Este compuesto se caracteriza por su estructura bicíclica única, que incluye un grupo funcional lactona. (-)-Parthenolida exhibe una variedad de actividades biológicas, incluyendo propiedades antiinflamatorias, anticancerígenas y antimicrobianas, lo que lo convierte en un tema de interés en la investigación farmacológica. Se sabe que inhibe la vía de señalización del factor nuclear kappa B (NF-κB), que juega un papel crucial en la inflamación y la progresión del cáncer. El compuesto se encuentra típicamente en forma líquida incolora a amarillo pálido y tiene un olor característico. Su solubilidad varía, siendo más soluble en disolventes orgánicos que en agua. Debido a sus posibles efectos terapéuticos, (-)-Parthenolida está siendo estudiado por su papel en el tratamiento de diversas condiciones, incluyendo migrañas y ciertos tipos de cáncer. Sin embargo, se necesita más investigación para comprender completamente sus mecanismos de acción y aplicaciones potenciales en medicina.
Fórmula:C15H20O3
InChI:InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11?,12-,13-,15+/m0/s1
Clave InChI:InChIKey=KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES:C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC\C(\C)=C\CC1)[H])[H])(O2)[H]
Sinónimos:- (1aR,4E,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,4Z,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (4E,7aS,10aS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (4Z)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- 2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
- Germacra-1(10),11(13)-dien-12-oic acid, 4,5α-epoxy-6β-hydroxy-, γ-lactone
- Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
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Parthenolide
CAS:Fórmula:C15H20O3Pureza:>97.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:248.32Parthenolide
CAS:Lactones, nesoiFórmula:C15H20O3Forma y color:White Crystalline PowderPeso molecular:248.14124Parthenolide
CAS:Fórmula:C15H20O3Pureza:≥ 98.0%Forma y color:White, off-white or pale yellow-brown powderPeso molecular:248.32Parthenolide
CAS:ParthenolideFórmula:C15H20O3Pureza:By hplc: 99.88% (Typical Value in Batch COA)Forma y color:SolidPeso molecular:248.3175Parthenolide
CAS:Parthenolide analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Fórmula:C15H20O3Pureza:(HPLC) ≥95%Forma y color:PowderPeso molecular:248.33(1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
CAS:Fórmula:C15H20O3Pureza:97%Forma y color:SolidPeso molecular:248.3175Parthenolide (Standard)
CAS:Parthenolide (Standard) is a reference standard for research and analysis in studies involving Parthenolide. Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB inhibitor and also specifically inhibits HDAC1 protein, but is inactive against other class I/II HDACs. Parthenolide has anti-inflammatory, anti-tumor, and anti-viral activities.Fórmula:C15H20O3Peso molecular:248.32Parthenolide
CAS:(3aS,9aR,10aR,10bS,E)-6,9a-Dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-oneFórmula:C15H20O3Pureza:97% HPLCPeso molecular:248.32Parthenolide
CAS:Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Fórmula:C15H20O3Pureza:98.19% - 99.46%Forma y color:SolidPeso molecular:248.32Parthenolide
CAS:LactoneFórmula:C15H20O3Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:248.32Parthenolide
CAS:Parthenolide is a sesquiterpene lactone, which is a bioactive compound derived from the plant species Tanacetum parthenium, commonly known as feverfew. This compound is primarily isolated from the aerial parts of the plant, where it is found in highest concentrations within the flowers and leaves. Parthenolide exerts its effects through several biochemical pathways, including the inhibition of nuclear factor-kappa B (NF-κB) signaling, which plays a critical role in inflammatory and immune responses. Additionally, it disrupts the activity of certain kinases and modulates the expression of genes involved in cell cycle regulation and apoptosis.Fórmula:C15H20O3Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:248.32 g/molParthenolide
CAS:M02322 - Parthenolide
Fórmula:C15H20O3Pureza:97%Forma y color:SolidPeso molecular:248.322
![(1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclod…](https://static.cymitquimica.com/products/IN/thumb/DA002A6V.jpg)
