CAS 20736-09-8

saikosaponina a

Descripción:

saikosaponina a es un saponina triterpenoide derivada principalmente de las raíces de la planta Bupleurum falcatum, que se utiliza comúnmente en la medicina tradicional. Se caracteriza por su estructura compleja, que presenta un esqueleto similar a un esteroide con múltiples moieties de azúcar adjuntas, lo que contribuye a su actividad biológica. saikosaponina a exhibe una variedad de propiedades farmacológicas, incluyendo efectos antiinflamatorios, hepatoprotectores e inmunomoduladores. Se ha estudiado por sus posibles aplicaciones terapéuticas en diversas condiciones, incluyendo enfermedades hepáticas y cáncer. Se sabe que el compuesto interactúa con las membranas celulares y puede influir en las vías de señalización celular, lo que puede subyacer a sus diversos efectos biológicos. Además, saikosaponina a ha mostrado potencial para mejorar la eficacia de ciertos agentes quimioterapéuticos. Sin embargo, su biodisponibilidad y metabolismo en el cuerpo humano son áreas de investigación en curso, ya que pueden afectar significativamente su potencial terapéutico. En general, saikosaponina a representa un producto natural prometedor con un interés farmacológico significativo.

Fórmula: C₄₂H₆₈O₁₃

InChI: InChI=1/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3/t21-,22-,23-,24-,25-,26+,27+,28+,29-,30+,31-,32-,33+,34+,35+,37+,38+,39-,40+,41-,42+/m1/s1

Clave InChI: InChIKey=KYWSCMDFVARMPN-FMIBPMOUSA-N

SMILES: C[C@]12[C@@]3(C4([C@@](CO3)([C@@H](O)C1)CCC(C)(C)C4)[H])C=C[C@]5([C@@]2(C)CC[C@@]6([C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@@H](C)O7)[C@]6(CO)C)[H])[H]

Sinónimos:

• (3Beta,4Alpha,16Beta)-13,28-Epoxy-16,23-Dihydroxyolean-11-En-3-Yl-6-Deoxy-3-O-Beta-D-Glucopyranosyl-Beta-D-Galactopyranoside
• (3beta,13alpha,16beta,17alpha)-16,23-dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-galactopyranoside
• Oleanane, β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
• Salikosaponin A
• sailkosaponin A
• β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-<smallcap>D</span>-glucopyranosyl-
• (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside
• β-D-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-
• Oleanane, β-D-galactopyranoside deriv.
• Saikosaponin A
• Thesaikosaponin A
• [(3β,4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside
• SAIKOSAPONIN A(RG)
• SABINYL ACETATE(RG)
• β-D-fucoside, (3β,4α,16β)-13,28-epoxy-16,23-
• Saikosaponin A, 98%, from Bupleurum chinense DC.
• SAILKOSAPONINS A
• dihydroxyolean-11-en-3-yl6-deoxy-3-O-β-D-
• [(4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3β-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside
• Saikosaponin a std.

SAIKOSAPONIN A CRS

CAS: 20736-09-8

SAIKOSAPONIN A CRS

Ref: 41-Y0001932

β-D-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-

CAS: 20736-09-8

Fórmula: C₄₂H₆₈O₁₃

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 780.9815

Ref: IN-DA002J0O

Saikosaponin A

CAS: 20736-09-8

Saikosaponin A

Fórmula: C₄₂H₆₈O₁₃

Pureza: ≥98%

Peso molecular: 780.98

Ref: 54-BUP02763

Saikosaponin A

CAS: 20736-09-8

Fórmula: C₄₂H₆₈O₁₃

Peso molecular: 780.98

Ref: 7W-GC0592

Saikosaponin A

CAS: 20736-09-8

Saikosaponin A (SSa), a main constituent of the Chinese herb Bupleurum chinense DC, has antiepileptic activity,could inhibit NMDA receptor current and persistent sodium current, and inhibit epileptiform discharges induced by 4AP in a dose-dependent manner.

Fórmula: C₄₂H₆₈O₁₃

Pureza: 95%~99%

Forma y color: Powder

Peso molecular: 780.993

Ref: BP-BP1238

Saikosaponin A

CAS: 20736-09-8

Fórmula: C₄₂H₆₈O₁₃

Pureza: >95.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 780.99

Ref: 3B-A3408

Saikosaponin A (Standard)

CAS: 20736-09-8

Saikosaponin A (Standard) is a reference standard for research and analysis in studies involving Saikosaponin A. Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase)-1 activity.

Fórmula: C₄₂H₆₈O₁₃

Forma y color: Solid

Peso molecular: 780.98

Ref: TM-TMSM-0961

Saikosaponin A

CAS: 20736-09-8

Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-

Fórmula: C₄₂H₆₈O₁₃

Pureza: 99.57% - 99.88%

Forma y color: White Solid

Peso molecular: 780.98

Ref: TM-T2768

Saikosaponin A

CAS: 20736-09-8

Natural glycoside

Fórmula: C₄₂H₆₈O₁₃

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 781

Ref: 5G-89526

Saikosaponin A

Producto controlado

CAS: 20736-09-8

Stability Hygroscopic
Applications Saikosaponin A was shown to exhibit anti-inflammatory activities by suppressing activation of NF-kB signaling pathway.
References Wu, S.J., et al.: Am. J. Chin. Med., 38, 99 (2010); Wu. S.J., et al.: J. Med. Food., 11, 224 (2008); Yoon, S.S., et al.: Neurosci. Lett., 529, 97 (2012); Lu, C.N., et al.: Int. Immunopharmacol., 14, 121 (2012);

Fórmula: C₄₂H₆₈O₁₃

Forma y color: Neat

Peso molecular: 780.98

Ref: TR-S083900

Saikosaponin A

CAS: 20736-09-8

Saikosaponin A is a triterpene saponin, which is a bioactive compound extracted from the roots of the Bupleurum species, primarily Bupleurum falcatum. As a phytochemical, it interacts with cell membranes to exert its effects. Saikosaponin A is known to modulate inflammatory pathways by inhibiting the production of pro-inflammatory cytokines and influencing the NF-κB signaling pathway. Additionally, it can enhance immune responses by regulating T-cell proliferation and differentiation.

Fórmula: C₄₂H₆₈O₁₃

Pureza: Min. 95%

Forma y color: White Off-White Powder

Peso molecular: 780.98 g/mol

Ref: 3D-OS09826

Saikosaponin a

CAS: 20736-09-8

Ref: BE-RMT10740